Results 261 to 270 of about 1,297,479 (340)

The Potential Contribution of the IL-37/IL-18/IL-18BP/IL-18R Axis in the Pathogenesis of Sjögren's Syndrome. [PDF]

Int J Mol Sci
Parisis D, Sarrand J, Soyfoo M.
europepmc   +1 more source

A Bio‐Responsive Hydrogel with Spatially Heterogeneous Structure for Treating Infectious Tissue Injuries

Advanced Science, EarlyView.
The hydrogel incorporates Ag⁺‐loaded Preyssler‐type polyoxometalates (POMs) that release Ag⁺ ions in response to endogenous Na⁺ ions, ensuring controlled antibacterial activity. The spatially heterogeneous structure, created through dual‐channel fiber stacking and in situ cross‐linking, enhances structural integrity and promotes tissue regeneration ...
Zongtai Li, Tao Yang, Xiaolei Li, Panchao Yin, Bo Yang, Dongying Li, Yan Wang, Wei Teng, Qianqian Yu, Weichang Li   +9 more
wiley   +1 more source

Benralizumab for acute thromboembolism in hypereosinophilic syndrome: a case report. [PDF]

Allergy Asthma Clin Immunol
Nagira D, Miyamoto S, Mizukoshi T, Yanagisawa A, Funauchi A, Kanaoka K, Yoshimura H, Jo T, Higashiguchi M, Naito Y, Shiroyama T, Tetsumoto S, Hirata H, Takeda Y, Kumanogoh A.   +14 more
europepmc   +1 more source

Synergistic Modulating of Mitochondrial Transfer and Immune Microenvironment to Attenuate Discogenic Pain

Advanced Science, EarlyView.
Gallic acid (GA) and copper ions self‐assemble to form nanoparticles, which are then modified with mitochondrial targeting peptides and gap junction modulator. These nanoparticles scavenge mitochondrial reactive oxygen species to induce M2 polarization and enhance intercellular mitochondrial transfer.
Xinzhou Wang, Zhenyu Guo, Linjie Chen, Jing Sun, Kenny Yat Hong Kwan, Morgan Jones, Yan Michael Li, Yangyang Hu, Xueqiang Wang, Pooyan Makvandi, Xiangyang Wang, Qiuping Qian, Yunlong Zhou, Aimin Wu   +13 more
wiley   +1 more source

Association between salivary immune markers and oral health conditions in pregnant women. [PDF]

Sci Rep
Alomeir N, Mao X, Yang R, Assery N, Quataert S, Seppo A, Lu X, Wu TT, Xiao J.   +8 more
europepmc   +1 more source

Genetically Engineered IL12/CSF1R‐Macrophage Membrane‐Liposome Hybrid Nanovesicles for NIR‐II Fluorescence Imaging‐Guided and Membrane‐Targeted Mild Photothermal‐Immunotherapy of Glioblastoma

Advanced Science, EarlyView.
A theranostic nanoplatform is formulated with NIR‐II emissive lipophilic cyanine dye IRC18 to intercalate into genetically engineered IL12/CSF1R‐macrophage membrane‐liposome hybrid nanovesicles, which assists to achieve blood–brain barrier crossing, glioblastoma targeting, NIR‐II fluorescence imaging, image‐guided membrane‐targeted mild photothermal ...
Pengfei Chen, Yue Liu, Haiyan Huang, Menglong Li, Hui Xie, Shubham Roy, Jingsi Gu, Jian Jin, Kai Deng, Lixin Du, Bing Guo   +10 more
wiley   +1 more source

<i>In-silico</i> proteomic analysis of the role of IL-4 and IL-10 in IVD degeneration: Protein-protein interaction networks for candidate prioritisation. [PDF]

Comput Struct Biotechnol J
Bermudez-Lekerika P, Gualdi F, Le Maitre CL, Piñero J, Oliva B, Gantenbein B.   +5 more
europepmc   +1 more source

Locoregional Immune Checkpoint Blockade and Remodeling of Lymph Nodes by Engineered Dendritic Cell‐Derived Exosomes for Suppressing Tumor Progression and Metastasis

Advanced Science, EarlyView.
The study develops engineered exosomes (EmDEX@GA) for locoregional immunomodulation of tumor‐draining lymph node (TDLN). EmDEX@GA can actively target to TDLN and remodel its immunosuppressive microenvironment through the synergistic effects of PD‐1/PD‐L1 blockade and STING pathway activation, subsequently enhance anti‐tumor immunity and suppress tumor ...
Yizhen Wang, Xiaomin Guo, Jingya Qin, Yifan Xue, Peng Zhang, Yadong Liu, Moyang Chen, Guanghao Zhu, Xinqiu Song, Lili Cheng, Bo Liu, Jie Liu, Jie Ren   +12 more
wiley   +1 more source

Statement of Retraction: Homeodomain-containing gene 10 contributed to breast cancer malignant behaviors by activating Interleukin-6/Janus kinase 2/Signal transducer and activator of transcription 3 pathway. [PDF]

Bioengineered
europepmc   +1 more source

A Self‐Assembling LYTAC Mediates CTGF Degradation and Remodels Inflammatory Tumor Microenvironment for Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
A CTGF‐LYTAC nanoplatform is developed to selectively degrade connective tissue growth factor (CTGF) in triple‐negative breast cancer (TNBC), inhibiting TGF‐β signaling and cell interactions in the tumor microenvironment (TME). This strategy effectively suppresses tumor growth and metastasis, outperforming antibody‐based therapy.
Jia‐Yi Lin, Ye Wu, Xiao‐Hui Liang, Min Tang, Xin Sun, Sheng‐Xin Lu, Jin‐Mei Jin, Xin Guo, Bei Wang, Hong‐Zhuan Chen, Wei‐Dong Zhang, Xin Luan   +11 more
wiley   +1 more source