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Immunotherapy with Interleukin-2 [PDF]
Chemotherapy is capable of producing durable responses in only a few types of advanced cancer and there is therefore an urgent need for alternative approaches to treatment. For decades, immunologists have held the hope that it might be possible to induce or augment a host antitumour response and produce immune-mediated disease regression.
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The promise of low-dose interleukin-2 therapy for autoimmune and inflammatory diseases
Nature reviews. Immunology, 2015D. Klatzmann, A. Abbas
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A function for interleukin 2 in Foxp3-expressing regulatory T cells
Nature Immunology, 2005J. Fontenot+3 more
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The phylogeny of interleukin-2
Developmental & Comparative Immunology, 1985Nicholas Cohen, David Watkins
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Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene
Cell, 1993B. Sadlack+5 more
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Interleukin-2 and the Interleukin-2 Receptor Complex
2015Glen N. Gaulton, Peter Williamson
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