Results 31 to 40 of about 56,790 (305)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Functional interlocked systems [PDF]
Chem. Soc. Rev., 2014 With the advent of supramolecular chemistry and later nanotechnology a great deal of research has been focused on new types of molecular structures, which are not held together by covalent bonds but by non-covalent mechanical interactions. Examples include the catenane, rotaxane, and knot interlocked structures.
van Dongen, S.F.H. +5 more
openaire +6 more sources
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Interlocking directorships and patenting coordination [PDF]
, 2020 The aim of this paper is to investigate the role interlocking directorships play in the patenting activities of UK companies and provide further insights into the channels through which this relationship emerges.
Efthyvoulou, G. +4 more
core +1 more source
Description of route dependencies for computer-based railway signalling systems
Archives of TransportEfficient and safe movement of trains on railway lines is assured by railway signalling systems. These systems assure safety of railway transport by preservation of dependencies.
Michał Grzybowski +2 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Mode II interlaminar shear behavior of needled/tufted interlocking composites
Journal of Industrial Textiles, 2023 The needled/tufted interlocking fabric is a new fabric structure. At present, the mode II interlaminar shear behavior of needled/tufted interlocking composite has not been clarified.
Jiao Li +4 more
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Research on Block between Subway Line Adjacent Interlocking Stations Based on Network Communication
机车电传动, 2020 In order to ensure the traffic safety between subway line adjacent stations, a blocking method based on network communication was proposed. The information transformed between the adjacent interlocking stations of the line and blocking principle was ...
Datao ZHANG
doaj