Results 161 to 170 of about 395,909 (339)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Policy coordination and financial intermediaries [PDF]

open access: yes
Summary of proceedings from the 1986 Fall Academic Conference sponsored by the Federal Reserve Bank of San FranciscoMonetary policy ; Monetary policy - United States ; International economic relations ; Bank supervision ; Financial ...
Carl E. Walsh, Michael C. Keeley
core  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Los intérpretes generales de Yucatán: hombres entre dos mundos

open access: yesEstudios de Cultura Maya, 2009
Este artículo se centra en un tipo importante de intermediarios en el Yucatán colonial, los intérpretes generales del Juzgado Privado de Indios de Yucatán.
Mark Lentz
doaj  

Insurance Intermediaries

open access: yesCECCAR Business Review
The insurance contract is concluded between the insured and the insurer. However, insurance relations may also involve other persons than the insured and the insurer, for example, the insurance contractor, the beneficiary, the person covered by the insurance, coinsurers, reinsurers, intermediaries who mediate the conclusion of the insurance contract ...
openaire   +2 more sources

Inflation taxes and inflation subsidies: Explaining the twisted relationship between inflation and output [PDF]

open access: yes
This paper studies the nature of monetary policy in a cash-in-advance model with indivisible labor and with financial intermediaries that provide loans for working capital. Monetary policy occurs through money injections either directly to families or to
George T. McCandless
core  

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

The National Fund for Workforce Solutions: A History of Collaborations [PDF]

open access: yes, 2008
Traces the history of cross-funder investment by local, national, private, and public funders in an initiative to strengthen and expand "workforce intermediaries" as a way to improve workforce training delivery through regional funding ...

core  

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

The importance of Intermediaries organizations in international R&D cooperation: an empirical multivariate study across Europe [PDF]

open access: yes
Despite the large number of publications related to business cooperation in R&D and the wide perception of the importance of intermediary institutions in the R&D cooperation process, empirical studies on its role are scarce, scattered and fragmented ...
Aurora A.C. Teixeira, Margarida Catarino
core  

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