Results 161 to 170 of about 80,350 (298)
Biography as the Missing Variable in Drug Development: A Case for Bio-Biographical Mechanistic Profiling. [PDF]
Clin Pharmacol TherHorwitz RI.
europepmc +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Developing an Antenatal Intervention to Improve Vaccine Uptake Using Parent, Patient and Public Involvement and Engagement in Northern Ireland. [PDF]
Health ExpectMcCarron SA, Patterson L, Hart N.
europepmc +1 more source
A model of shadow banking [PDF]
We present a model of shadow banking in which financial intermediaries originate and trade loans, assemble these loans into diversified portfolios, and then finance these portfolios externally with riskless debt. In this model: i) outside investor wealth
Andrei Shleifer +2 more
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Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Impact on hospitals of price reductions for physician-administered biologics. [PDF]
Health Aff SchRobinson JC +3 more
europepmc +1 more source
Financial Intermediaries [PDF]
This is an essay on Financial Intermediaries written for the New Palgrave.
James Tobin
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Recent Mycobacterium tuberculosis Transmission, United States, 2018-2022. [PDF]
Emerg Infect DisZubairi R.
europepmc +1 more source
Financial Intermediaries and Transaction Costs [PDF]
We present an overlapping generations model with spatial separation and agents who face unsystematic liquidity risk. In a pure exchange economy, agents engage in life cycle portfolio rebalancing.
Augusto Hasman +2 more
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