Results 81 to 90 of about 21,739 (292)

High‐Throughput Digital Decoding of Vascular Heterogeneity in Patient‐Specific Tumor Microenvironments

Advanced Healthcare Materials, EarlyView.
ABSTRACT Quantitative characterization of vascular heterogeneity in complex microphysiological systems (MPS), particularly within patient‐derived tumor microenvironments, remains a major challenge for scalable disease modeling and therapeutic evaluation.
Jungseub Lee, Wooju Park, Sujin Hyung, Sangmin Jung, Kyungho Lee, Junseok Jeon, Noo Li Jeon, Jeeyun Lee, Hye Ryoun Jang, Jihoon Ko   +9 more
wiley   +1 more source

Primordial black holes in non-linear perturbation theory [PDF]

, 2009
PhDThe thesis begins with a study of the origin of non-linear cosmological fluctuations. In particular, a class of models of multiple field inflation are considered, with specific reference to those cases in which the non-Gaussian correlation functions
Hidalgo-Cuellar, Juan Carlos
core  

Discovering intermediate-mass black hole lenses through gravitational wave lensing [PDF]

, 2019
© 2018 American Physical Society. Intermediate-mass black holes are the missing link that connects stellar-mass to supermassive black holes and are key to understanding galaxy evolution.
Herrera-Martín A, Broadhurst T, Li TGF, Hannuksela OA, Diego JM, Lai KH   +5 more
core   +1 more source

A Lightweight, 3D‐Printable, Low‐Cost, “One‐Click” Dorsal Skin Window for High‐Quality Long‐Term Multimodal Subcutaneous Tumor Imaging

Advanced Healthcare Materials, EarlyView.
An innovative, lightweight 3D‐printed skinfold chamber system is presented for long‐term intravital imaging. This affordable, biocompatible platform simplifies surgical implantation and allows high‐resolution, multimodal visualization of the tumor microenvironment for up to four weeks.
Iván Cortés Domínguez, Xabier Morales Urteaga, Maider Esparza, Lucía Grande, Ainhoa Urbiola, Cristina Ederra, Tomas Muñoz Santoro, Beatrice Pinci, Alvaro Teijeira, Carlos Ortiz de Solórzano   +9 more
wiley   +1 more source

Higher-dimensional black holes: Braneworld stars and Hawking radiation. [PDF]

, 2007
In this thesis two aspects of braneworld models are studied. A new attempt at finding the metric of a braneworld black hole within the second Randall-Sundrum model is explored. Branes containing distributions of perfect fluid are embedded in a variety of
Creek, Simon
core  

Topics in Core-Collapse Supernova Theory: The Formation of Black Holes and the Transport of Neutrinos [PDF]

, 2012
Core-Collapse Supernovae are one of the most complex astrophysical systems in the universe. They deeply entwine aspects of physics and astrophysics that are rarely side by side in nature.
O'Connor, Evan Patrick
core   +1 more source

Properties of “Lite” Intermediate-mass Black Hole Candidates in LIGO-Virgo’s Third Observing Run

The Astrophysical Journal Letters
Over a hundred gravitational-wave (GW) detections and candidates have been reported from the first three observing runs of the Advanced LIGO-Virgo-KAGRA (LVK) detectors. Among these, the most intriguing events are binary black hole mergers that result in
Krystal Ruiz-Rocha, Anjali B. Yelikar, Jacob Lange, William Gabella, Robert A. Weller, Richard O’Shaughnessy, Kelly Holley-Bockelmann, Karan Jani   +7 more
doaj   +1 more source

Intermediate-mass Black Holes’ Effects on Compact Object Binaries

The Astrophysical Journal, 2020
Abstract Although their existence is not yet confirmed observationally, intermediate-mass black holes (IMBHs) may play a key role in the dynamics of galactic nuclei. In this paper, we neglect the effect of the nuclear star cluster itself and investigate only how a small reservoir of IMBHs influences the secular dynamics of stellar-mass ...
Barnabás Deme, Yohai Meiron, Bence Kocsis   +2 more
openaire   +3 more sources

Engineered Microvascular Model of the Blood–Brain–Tumor Barrier Reveals Endothelial Remodeling in Diffuse Midline Glioma

Advanced Healthcare Materials, EarlyView.
We developed a patient‐derived, functional microfluidic model of the diffuse midline glioma (DMG) blood–brain–tumor barrier (BBTB) comprised of endothelial cells, astrocytes, pericytes, and tumor cells. The system forms perfusable microvasculature, reveals the BBTB retains vascular integrity, identifies DMG‐specific transcriptomic changes distinct from
Kimberly R. Bennett, Yann S. Vanrobaeys, Tessy Teboh, Zakiya Smith, Anderson Scott, Cynthia Hajal, Paula T. Hammond, Joelle P. Straehla   +7 more
wiley   +1 more source

Explorations of four and five dimensional black hole spacetimes [PDF]

, 2009
This thesis concentrates on four and five dimensional black holes and their associated geodesies. Some coordinate charts are presented, which are useful in the analysis of both static and rotating black holes, and their mathematical properties ...
Hoskisson, James
core