Results 91 to 100 of about 3,959,588 (324)

SPATIAL DISTRIBUTION OF LYMNAEIDAE (MOLLUSCA, BASOMMATOPHORA), INTERMEDIATE HOST OF Fasciola hepatica LINNAEUS, 1758 (TREMATODA, DIGENEA) IN BRAZIL

Revista do Instituto de Medicina Tropical de São Paulo, 2014
Snails of the family Lymnaeidae act as intermediate hosts in the biological cycle of Fasciola hepatica, which is a biological agent of fasciolosis, a parasitic disease of medical importance for humans and animals. The present work aimed to update and map
C. Medeiros, R. G. Scholte, S. D’ávila, R. Caldeira, O. Carvalho   +4 more
semanticscholar   +1 more source

Intermediate Hosts of Angiostrongylus cantonensis in Tenerife, Spain

PLOS ONE, 2015
The nematode Angiostrongylus cantonensis is the causative agent of human angiostrongyliasis, the main clinical manifestation of which is eosinophilic meningitis. Although this parasite has been found recently in its definitive rat host in Tenerife (Canary Islands, Spain), showing a widespread distribution over the north-east part of the island, there ...
Martin-Alonso, Aarón, Abreu Yanes, Estefanía, Feliu José, Carlos, Mas-Coma, Santiago, Bargues, María Dolores, Valladares, Basilio, Foronda, Pilar   +6 more
openaire   +5 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Differential spatial repositioning of activated genes in Biomphalaria glabrata snails infected with Schistosoma mansoni [PDF]

, 2014
Copyright @ 2014 Arican-Goktas et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and
A Zarjou, AE Lockyer, AE Lockyer, AE Lockyer, AN Miller, C Li, C Perrin, CM Adema, CS Richards, D Zink, E Odoemelam, EC Odoemelam, EV Volpi, H Bierne, HA Foster, HA Foster, Halime D. Arican-Goktas, I Szczerbal, IS Mehta, JA Croft, JM Bridger, Joanna M. Bridger, KJ Livak, KJ Meaburn, KJ Meaburn, KK1 Geyer, L Chitsulo, LA Hertel, M Cremer, M Knight, M Knight, Malcolm K. Jones, Matty Knight, MG Castillo, N Raghavan, N Raghavan, P Fraser, PF Basch, S Fneich, S Jin, SD Bernal, TP Yoshino, UK Hahn, UK Hahn, W Ittiprasert, W Ittiprasert, W Ittiprasert, Wannaporn Ittiprasert, Y Hu   +48 more
core   +3 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Advances in Detecting Cystic Echinococcosis in Intermediate Hosts and New Diagnostic Tools: A Literature Review

Veterinary Sciences
Cystic echinococcosis (CE) is a zoonotic disease affecting humans and animals. Despite a lack of clarity about many details of parasite–intermediate host interactions, the nature of the immune responses triggered by hydatid infection has revealed new ...
Ashkan Hajjafari, Soheil Sadr, Cinzia Santucciu, Giovanna Masala, Mansour Bayat, Narges Lotfalizadeh, Hassan Borji, Soroush Partovi Moghaddam, Khashayar Hajjafari   +8 more
doaj   +1 more source

Influence of physico-chemical parameters on the intermediate host of Schistosoma haematobium and Schistosoma mansoni in Makwaye and Kubanni Reservoirs, Zaria, Nigeria

Journal of Advanced Veterinary and Animal Research, 2017
Objective: This research was conducted to determine the influence of physico-chemical characteristics on diversity of the intermediate host of schistosomes in Makwaye and Kubanni reservoirs, Zaria, Nigeria.
Abdullahi Bala Alhassan, Muhammad Lawal Balarabe, Ibrahim Madu Katsallah Gadzama, Sha’aba Ramatu Idris, Yunusa Adamu Wada, Abdullateef Yusuf   +5 more
doaj   +1 more source

Evolution of BCGs structural parameters in the last $\sim$6 Gyr: feedback processes versus merger events

, 2010
We present results on the evolution in the last 6 Gyr of the structural parameters of two samples of brightest cluster galaxies (BCGs). The nearby sample of BCGs consist on 69 galaxies from the WINGS survey spanning a redshift range of 0.04$
A. Cava, Aguerri, Aguerri, Aragón-Salamanca, Arnaboldi, Arnaboldi, Ascaso, B. Ascaso, Bernardi, Bower, Burke, Caon, Coziol, D. Bettoni, Daddi, Dubinski, Ebeling, Fabian, Fan, Fasano, Gonzalez, Graham, Gutiérrez, J. A. L. Aguerri, J. Varela, Kim, Kormendy, Lin, Lin, M. D'Onofrio, M. Moles, Merritt, Miley, Mullis, Nelson, Reiprich, Ryan, Silich, Stanford, Stott, Sérsic, Tenorio-Tagle, Trujillo, van Dokkum, van Dokkum, Vikhlinin, Vikhlinin   +46 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Wandering Black Holes in Bright Disk Galaxy Halos

, 2010
We perform SPH+N-body cosmological simulations of massive disk galaxies, including a formalism for black hole seed formation and growth, and find that satellite galaxies containing supermassive black hole seeds are often stripped as they merge with the ...
Barth, Brooks, Brooks, Devecchi, Di Matteo, Fan, Filippenko, Fujita, Governato, Greene, Gross, Jonker, Kazantzidis, Krolik, Leitherer, Leroy, Madau, Mayer, Meylan, Schneider, Spergel, Stadel, Swartz, Ulvestad, Volonteri, Wiersema   +25 more
core   +1 more source