Results 131 to 140 of about 3,959,588 (324)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

On the Role of Dewetting Transitions in Host-Guest Binding Free Energy Calculations. [PDF]

, 2013
We use thermodynamic integration (TI) and explicit solvent molecular dynamics (MD) simulation to estimate the absolute free energy of host-guest binding.
Baron, Riccardo, de Oliveira, César Augusto F, Fajer, Mikolai, McCammon, J Andrew, Ortiz-Sánchez, Juan Manuel, Rogers, Kathleen E   +5 more
core  

Evolution of the spectral curvature in the ULX Holmberg II X-1

, 2012
Ultraluminous X-ray sources (ULXs) are interesting systems as they can host intermediate mass black holes. Alternatively, ULXs can represent stellar-mass black holes accreting at super-Eddington rates.
Abramowicz, Beloborodov, Berghea, Colbert, Dewangan, Ebisuzaki, F. Grisé, Farrell, Farrell, Feng, Feng, Feng, Feng, Ferrarese, Gierliński, Gladstone, Goad, Godet, Gonçalves, Grimm, Grisé, Heil, J. J. E. Kajava, J. Poutanen, Kaaret, Kaaret, Kaaret, Kaaret, Kaaret, Kajava, Karachentsev, King, Kong, Kong, Makishima, Mapelli, McClintock, Middleton, Miller, Miller, Mineo, Miyaji, Ohsuga, Ohsuga, P. Kaaret, Portegies Zwart, Poutanen, Roberts, S. A. Farrell, Servillat, Shakura, Soria, Stobbart, Strohmayer, Swartz, Swartz, Tsunoda, Vierdayanti, Watarai, Wilms, Winter   +60 more
core   +1 more source

Spatial distribution of Biomphalaria spp., the intermediate host snails of Schistosoma mansoni, in Brazil.

Geospatial Health, 2012
Schistosomiasis mansoni remains an important parasitic disease of man, endemic in large parts of sub-Saharan Africa, the Middle East, South America and the Caribbean.
Ronaldo G C Scholte, O. S. Carvalho, J. Malone, J. Utzinger, P. Vounatsou   +4 more
semanticscholar   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Echinococcus species in wildlife

International Journal for Parasitology: Parasites and Wildlife
Transmission of Echinococcus spp. in life cycles that involve mainly wildlife is well recognized for those species with small mammals as intermediate hosts (e. g. E. multilocularis), as well as for E. felidis and the ‘northern’ genotypes of E. canadensis
Thomas Romig, Marion Wassermann
doaj   +1 more source

Nematodes from Achatina fulica Bowdich, 1822 (Mollusca: Gastropoda) in Argentina

Helminthologia, 2016
The aim of this study is to describe the nematode cysts and larvae found in Achatina fulica, the giant African snail, in the northeast of Argentina. A total of 373 snails were collected from the cities of Puerto Iguazú and Corrientes.
Valente R., Diaz J. I., Lorenti E., Salomón O. D., Navone G. T.   +4 more
doaj   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

The stellar content of low redshift radio galaxies from near-infrared spectroscopy

, 2009
We present medium spectral resolution near-infrared (NIR) HK-band spectra for 8 low redshift (z2.29microns), were measured. To characterize the age of the populations, the measured EWs of the absorption features were fitted with the corresponding ...
Ali, Aretxaga, Bellamy, Bendo, Bressan, Bruzual, Carretero, Cavaliere, Cesetti, Falomo, Fasano, Fioc, Fremaux, Frogel, Frogel, Förster Schreiber, Govoni, Heidt, Holt, Hyvönen, Hyvönen, J. K. Kotilainen, J. Reunanen, Jahnke, James, Kennicutt, Kleinmann, Kojima, Kotilainen, Kotilainen, Kuntschner, Longhetti, Mannucci, Maraston, Mayya, Merrill, Mobasher, Nolan, Oke, Oliva, Oliva, Origlia, Origlia, Peletier, R. Falomo, Raimann, Ramirez, Sanchez, Schade, Silva, Springel, Strateva, T. Hyvönen, Tadhunter, Tadhunter, Tantalo, Trager, Vázquez, Wallace, Wallace, Wills, Worthey, Worthey, Yamada, Örndahl   +64 more
core   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source