Results 101 to 110 of about 453,245 (300)
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Concentrated, Gradient Electrolyte Design for Superior Low-Temperature Li-Metal Batteries
BatteriesImproving the low-temperature performance of lithium-ion batteries is critical for their widespread adoption in cold environments. In this study, we designed a novel LHCE featuring a solvent polarity gradient, designed to maximize both room- and low ...
Jason S. Packard +2 more
doaj +1 more source
Materials & Design, 2019 The development of bulk materials with ferroelectric/antiferroelectric (FE/AFE) phase transitions is of importance for meeting the needs of advanced electronic equipment. Here, we report a (1 − x)Pb(Lu0.5Nb0.5)O3-xPbTiO3 (abbreviated as PLNT100x) system,
Xiaoming Yang +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Effect of Reaction Media on Photosensitized [2+2]‐Cycloaddition of Cinnamates
ChemistryOpen, 2020 The outcome of photosensitized [2+2]‐cycloaddition reactions of various cinnamates has been compared in different reaction media, including homogeneous organic solutions under inert conditions, degassed water, and aerated physical gels.
Alex Abramov +2 more
doaj +1 more source
XMM-Newton and Optical Observations of Cataclysmic Variables from SDSS
, 2009 We report on XMM-Newton and optical results for 6 cataclysmic variables that were selected from Sloan Digital Sky Survey spectra because they showed strong HeII emission lines, indicative of being candidates for containing white dwarfs with strong ...
Anjum Mukadam +20 more
core +1 more source
An alternative model of the magnetic cataclysmic variable V1432 Aquilae (=RX J1940.1-1025) [PDF]
, 1997 V1432 Aql is currently considered to be an asynchronous AM Her type system, with an orbital period of 12116.3 s and a spin period of 12150 s. I present an alternative model in which V1432 Aql is an intermediate polar with disk overflow or diskless ...
Allan A. +17 more
core +3 more sources
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Plasticity of intermediate mechanics students’ coordinate system choice
Physical Review Special Topics. Physics Education Research, 2008 We investigate the interplay between mathematics and physics resources in intermediate mechanics students. In the mechanics course, the selection and application of coordinate systems is a consistent thread.
Eleanor C. Sayre, Michael C. Wittmann
doaj +2 more sources
The Intriguing Nature of the Cataclysmic Variable SS Cygni
Acta Polytechnica, 2012 The classification of SS Cyg as a dwarf nova (DN), a subclass of the non–magnetic (NM) cataclysmic variable (CV) has been considered by most of the community as well established because of a paper appeared in Nature (Bath & van Paradijs, 1983), which was
F. Giovannelli, L. Sabau-Graziati
doaj