Results 51 to 60 of about 7,666,987 (279)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Direct experimental evidence of time-temperature superposition at finite strain for an amorphous polymer network [PDF]

, 2015
The time-temperature superposition property of an amorphous polymer acrylate network is characterized at infinitesimal strain by standard dynamic mechanical analysis tests.
GILORMINI, Pierre, DIANI, Julie, ARRIETA, Juan Sebastian, Arrieta, J.S., Arrieta, Juan Sebastain   +4 more
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Full-field strain measurement and identification of composites moduli at high strain rate with the virtual fields method [PDF]

, 2010
The present paper deals with full-field strain measurement on glass/epoxy composite tensile specimens submitted to high strain rate loading through a split Hopkinson pressure bar (SHPB) device and with the identification of their mechanical properties ...
MOULART, Raphaël, M. R. Wisnom, R. Moulart, HALLETT, Stephen R., Wisnom, M. R., Pierron, F., Hallett, S. R., S. R. Hallett, Moulart, R., F. Pierron, WISNOM, Michael R., Moulart, R, Hallett, SR, Pierron, F, Wisnom, MR, PIERRON, Fabrice   +15 more
core   +1 more source

Intermediate temperature tensile behavior and processing map of a spray formed 7075 aluminum alloy

Journal of Materials Research and Technology, 2023
The intermediate temperature deformation behavior and microstructural evolution of a spray formed 7075 Al alloy were performed at temperatures 60–120 °C with strain rates 0.00001–0.1 s−1.
Yaocheng Zhang, Ziyun Fan, Yangyang Li, Jiawen Zhong, Song Pang, Hiromi Nagaumi   +5 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Computational modeling of dynamic mechanical properties of pure polycrystalline magnesium under high loading strain rates

EPJ Web of Conferences, 2015
Computational simulations were performed to investigate the dynamic mechanical behavior of pure polycrystalline magnesium under different high loading strain rates with the values of 800, 1000, 2000, and 3600 s−1.
Li Qizhen
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Experimental and analytical study on the compressive behavior of PMI foam with different densities and cell sizes under intermediate strain rates

Polymer Testing
Polymethacrylimide (PMI) foam materials have great potential for applications in the field of protective energy absorption owing to their superior compressive properties.
Peilin Zhu, Jili Rong, Shenglong Wang, Zichao Chen   +3 more
doaj   +1 more source