Results 51 to 60 of about 14,495 (295)

New insights into the genetic component of non-infectious uveitis through an Immunochip strategy [PDF]

open access: yes, 2016
Background: Large-scale genetic studies have reported several loci associated with specific disorders involving uveitis. Our aim was to identify genetic risk factors that might predispose to uveitis per se, independent of the clinical diagnosis, by ...
Adán, Alfredo   +23 more
core   +2 more sources

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and One‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

open access: yesArthritis Care &Research, Accepted Article.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension‐phase). During part 1, three doses were assessed in two weight groups (Group A/B: ≥30–60 kg/≥10–<
Fabrizio De Benedetti   +19 more
wiley   +1 more source

Association between visual function response and reduction of inflammation in noninfectious uveitis of the posterior segment [PDF]

open access: yes, 2017
PURPOSE. To examine the association between visual function response (VFR) and inflammation reduction in active noninfectious uveitis of the posterior segment (NIU-PS). METHODS.
Bodaghi, Bahram   +6 more
core   +3 more sources

Rheumatologic Manifestations of Patients With Type B Insulin Resistance

open access: yesArthritis Care &Research, EarlyView.
Objective The objectives of this study were to identify laboratory and clinical features associated with type B insulin resistance (TBIR), a rare condition caused by autoantibodies that inhibit the insulin receptor, most frequently occurring in the setting of systemic lupus erythematosus (SLE), and to increase awareness of this rare, life‐threatening ...
S. Amara Ogbonnaya   +4 more
wiley   +1 more source

[Intermediate uveitis].

open access: yesKlinika oczna, 1992
Presented are contemporary opinions on the etiopathogenesis, epidemiology and clinical course of intermediate uveitis. Discussed are also the diagnostics and the trials of treatment of this condition.
M, Porubská   +3 more
openaire   +3 more sources

Efficacy and Safety of Adalimumab in Pediatric Non-infectious Non-anterior Uveitis: Real-life Experience From the International AIDA Network Uveitis Registry

open access: yesOphthalmology and Therapy, 2023
Introduction Scientific evidence of the effectiveness of the tumor necrosis factor inhibitor adalimumab (ADA) in pediatric patients with non-infectious non-anterior uveitis is still limited. The aim of this study is to investigate the therapeutic role of
Antonio Vitale   +30 more
doaj   +1 more source

Granuloma de coróide secundário a membrana neovascular sub-retiniana em uveíte intermediária: relato de casos [PDF]

open access: yes, 2008
Choroidal neovascularization is a very rare complication in intermediate uveitis. A 27-year-old female patient diagnosed with intermediate uveitis two years ago.
Garcia Filho, Carlos Alexandre de Amorim   +3 more
core   +2 more sources

Genetic Diagnosis and Discovery Enabled by Large Language Models

open access: yesAdvanced Science, EarlyView.
We demonstrate that large language models (LLMs) can facilitate genetic diagnosis and discovery. LLMs were used to solve four types of genetic problems of sequentially increased complexity. An LLM‐based pipeline could analyze genetic variants in the genomic sequences of human hearing loss or rare genetic disease patients and assist in identifying ...
Tao Tu   +25 more
wiley   +1 more source

Relationship of the ocular surface temperature with the clinical features of induced non-infectious anterior and intermediate uveitis in rabbits

open access: yesJournal of Ophthalmology, 2020
Background: It is an important challenge to develop objective methods for assessing intraocular inflammation. Purpose: To assess the relationship of the ocular surface temperature in the projection of the ciliary body with the clinical signs of ...
O. Dorokhova, O. Zborovska, Men Guanjun
doaj   +1 more source

Cytokine Profiles in Toxoplasmic and Viral Uveitis [PDF]

open access: yes, 2017
BackgroundUveitis is a major cause of visual impairment throughout the world. Analysis of cytokine profiles in aqueous humor specimens may provide insight into the physiopathological processes that underly retinal damage in this context MethodsUsing a ...
Abdelrahman, Tamer   +14 more
core  

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