Results 181 to 190 of about 522,439 (294)

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Development and validation of the dysarthria impact scale: a patient-reported outcome for motor speech disorders. [PDF]

J Neurol
Vogel AP, Graf L, Weiß M, Chan CSJ, Hepworth G, Synofzik M.   +5 more
europepmc   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Intermediate version of the system

Release of the 1st (intermediate) version of the platform with all the basic functionalities and services that will allow the use of the platform for educational purposes.
openaire   +1 more source

Impact of Outdated Clinical and Laboratory Standards Institute (CLSI) Breakpoint Implementation on Antimicrobial Susceptibility Interpretation: A Retrospective Analytical Study. [PDF]

Cureus
Goyal N, Gangar S, Ramakrishnan B, Goma M, Sj G, Das S.   +5 more
europepmc   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

DICE simulation tools - Intermediate version

This deliverable is the implementation (with an accompanying document) of the verification tool to evaluate safety of data-intensive applications, as developed in T3.3. Besides releasing code, it will feature a report documenting the implementation.
openaire   +1 more source

Neuronal Features of Visual Attention in the Mouse Superior Colliculus Depend on Learned Behavioral Relevance. [PDF]

J Neurosci
Wang L, Quaia C, Elliott K, Cover KK, Krauzlis RJ.   +4 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

DICE verification tools - Intermediate version

This deliverable is the implementation (with an accompanying document) of the verification tool to evaluate safety of data-intensive applications, as developed in T3.3. Besides releasing code, it will feature a report documenting the implementation.
openaire   +1 more source