Results 231 to 240 of about 522,439 (294)

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Second version of Intermediate hardware prototypes

Intermediate report about the implementation status and progress report toward the achievement of the EVOLVEs ...
openaire   +1 more source

Evaluation of large language models in assigning PI-RADS v2.1 categories for prostate MRI reports. [PDF]

BMC Urol
Akdal Dolek B, Besler MS.
europepmc   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Pathological convergence of a bacterial plant pathogen is associated with the horizontal transfer of an effector-containing mobile element. [PDF]

BMC Genomics
Bull EM, Agarwal V, Dillon MM.
europepmc   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

Intermediate version of the Policy Brief

This deliverable will follow the EC policy brief template summarizing insights and learnings on modelling framework to assess and optimise the environmental and socio-economic performance of five bio-based sectors: construction, woodworking, textile, pulp and paper, and bio-chemicals for policy-makers.
openaire   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Re-Value Impact Model (intermediate version)

The intermediate version of the Re-Value impact model. It will capture the operationalisation of the triangle of sustainability, inclusion and aesthetics towards a climate-neutral future and will incorporate the results from the Innovation Cycles (T1.2-1.4) and the monitoring of impact (T7.2), and be qualified with the 9 cities.
openaire   +1 more source

Comparison of Visual Performance and Patient Satisfaction Between Two Trifocal Intraocular Lenses: A Prospective, Paired-Eye Comparative Study. [PDF]

Clin Ophthalmol
Kang S, Arsenault SM, O'Brien RC, Chatzea MS, Zarei-Ghanavati S, Beniz LAF, Yoo SH.   +6 more
europepmc   +1 more source