Results 41 to 50 of about 31,231 (266)

A Rare Case of Intermittent Claudication Associated with Impaired Arterial Vasodilation

Case Reports in Vascular Medicine, 2017
Exercise-related intermittent claudication is marked by reduced blood flow to extremities caused by either stenosis or impaired vascular function. Although intermittent claudication is common in the elderly, it rarely occurs in the young and middle-aged ...
J. J. Posthuma, K. D. Reesink, M. Schütten, C. Ghossein, M. E. Spaanderman, H. ten Cate, G. Schep   +6 more
doaj   +1 more source

Barriers and enablers to walking in individuals with intermittent claudication: a systematic review to conceptualize a relevant and patient-centered program [PDF]

, 2018
Background: Walking limitation in patients with peripheral arterial disease (PAD) and intermittent claudication (IC) contributes to poorer disease outcomes.
Abaraogu, Ukachukwu, Brittenden, Julie, Dall, Philippa, Ezenwankwo, Elochukwu, Harwood, Amy, Seenan, Chris, Stuart, Wesley, Tew, Garry   +7 more
core   +5 more sources

Protocol for the Stimulating β3-Adrenergic Receptors for Peripheral Artery Disease (STAR-PAD) trial: a double-blinded, randomised, placebo-controlled study evaluating the effects of mirabegron on functional performance in patients with peripheral arterial disease

BMJ Open, 2021
Introduction There is currently only one approved medication effective at improving walking distance in people with intermittent claudication. Preclinical data suggest that the β3-adrenergic receptor agonist (mirabegron) could be repurposed to treat ...
Clara Chow, Anthony C Keech, Laurent Billot, Sanjay Patel, Kristen J Bubb, Stuart M Grieve, Gemma A Figtree, Jonathan Golledge, Jason A Harmer, Meghan Finemore, Sarah Joy Aitken, Zara S Ali, Rebecca Mister, Michael P Gray, Naomi Hamburg, Vikram Puttaswamy   +15 more
doaj   +1 more source

Buflomedil for intermittent claudication [PDF]

, 2013
Background : Intermittent claudication (IC) is pain caused by chronic occlusive arterial disease, that develops in a limb during exercise and is relieved with rest. Buflomedil is a vasoactive agent used to treat peripheral vascular disease.
De Backer, Tine, Vander Stichele, Robert
core   +2 more sources

Neuropsychiatric symptoms in patients with aortic aneurysms. [PDF]

PLoS ONE, 2011
BACKGROUND: Emerging evidence suggests that vascular disease confers vulnerability to a late-onset of depressive illness and the impairment of specific cognitive functions, most notably in the domains of memory storage and retrieval.
Bernhard T Baune, Steven J Unwin, Frances Quirk, Jonathan Golledge   +3 more
doaj   +1 more source

Silence of the limbs: pharmacological symptomatic treatment of intermittent claudication [PDF]

, 2010
Several oral "vasoactive" drugs claim to increase walking capacity in patients with intermittent claudication (IC). Naftidrofuryl, cilostazol, buflomedil, and pentoxifylline are the most studied molecules.
De Backer, Gui, De Backer, Tine, De Buyzere, Marc, Van Bortel, Lucas, Vander Stichele, Robert   +4 more
core   +1 more source

The effect of sequential intermittent pneumatic compression of foot and calf on popliteal artery mean systolic blood flow in patients with intermittent claudication

Asian Journal of Surgery, 2012
Objective: To determine the effect of intermittent pneumatic foot and calf compression on popliteal artery mean systolic blood flow in patients with intermittent claudication. The secondary objective was to determine the change in blood flow with posture.
Daphne Anthonysamy, Zainal Ariffin Azizi, Hafizan Mohd Tajri   +2 more
doaj   +1 more source

Efficacy and Safety of Adjunctive Cilostazol to Clopidogrel‐Treated Diabetic Patients With Symptomatic Lower Extremity Artery Disease in the Prevention of Ischemic Vascular Events

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background Type 2 diabetes mellitus is a risk factor for lower extremity arterial disease. Cilostazol expresses antiplatelet, anti‐inflammatory, and vasodilator actions and improves the claudication intermittent symptoms. We investigated the efficacy and
Kallirroi Kalantzi, Nikolaos Tentolouris, Andreas J. Melidonis, Styliani Papadaki, Michail Peroulis, Konstantinos A. Amantos, George Andreopoulos, George I. Bellos, Dimitrios Boutel, Magdalini Bristianou, Dimitrios Chrisis, Nikolaos A. Dimitsikoglou, John Doupis, Chrysoula Georgopoulou, Stergios A. Gkintikas, Styliani Iraklianou, Κonstantinos Kanellas, Kalliopi Kotsa, Theocharis Koufakis, Maria Kouroglou, Anastasios G. Koutsovasilis, Leonidas Lanaras, Eirini Liouri, Charalampos Lixouriotis, Akrivi Lykoudi, Efthymia Mandalaki, Evanthia Papageorgiou, Nikolaos Papanas, Spyridon Rigas, Maria I. Stamatelatou, Ioannis Triantafyllidis, Aikaterini Trikkalinou, Aikaterini N. Tsouka, Ourania Zacharopoulou, Christos Zoupas, Ioannis Tsolakis, Alexandros D. Tselepis   +36 more
doaj   +1 more source

A systematic review of exercise testing in patients with intermittent claudication: A focus on test standardisation and reporting quality in randomised controlled trials of exercise interventions.

PLoS ONE, 2021
A systematic review was conducted to identify the range of terminology used in studies to describe maximum walking distance and the exercise testing protocols, and testing modalities used to measure it in patients with intermittent claudication.
Stefan T Birkett, Amy E Harwood, Edward Caldow, Saïd Ibeggazene, Lee Ingle, Sean Pymer   +5 more
doaj   +1 more source

Mechanically Robust Biodegradable Stents With Theragenerative Vascular Responses via Combined 3D Printing and Janus Nanoengineering

Advanced Science, EarlyView.
This work introduces a theragenerative 3D‐printed biodegradable stent with Janus nanoarchitecture for spatially controlled vascular healing. A luminal tantalum ion–implanted surface accelerates endothelialization and hemocompatibility, while an abluminal sirolimus/poly‐L‐lactic acid–tantalum layer provides sustained drug release and suppresses smooth ...
Jong Hwa Seo, Dong‐Sung Won, Hyun Lee, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Chan Ho Moon, Ji Won Kim, Yubeen Park, Minho Kang, Dong Yun Lee, Donghyun Lim, Kisuk Yang, Gi Doo Cha, Soo‐Hong Lee, Tae‐Sik Jang, Seokbeom Kim, Jun‐Kyu Park, Jung‐Hoon Park, Hyun‐Do Jung   +19 more
wiley   +1 more source