Results 41 to 50 of about 13,401,879 (305)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
The external and internal context [PDF]
The practice of designing, delivering and evaluating learning and development occurs primarily in organisational contexts. It is therefore necessary for practitioners to have an understanding of factors influencing those contexts.
Mills, Sophie +3 more
core
External and internal pricing in multidivisional firms
Multidivisional firms frequently rely on external market prices in order to value internal transactions across profit centers. This paper examines market-based transfer pricing when an upstream division has monopoly power in selling a proprietary ...
Baldenius, Tim, Reichelstein, Stefan
core +1 more source
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
The movement kinematics and learning strategies associated with adopting different foci of attention during both acquisition and anxious performance [PDF]
Research suggests that implicit strategies adopted during learning help prevent breakdown of automatic processes and subsequent performance decrements associated with the presence of pressure.
Khan, M.A. +15 more
core +1 more source
Internal control of the organization and its external audit
Internal control is one of the least studied types of financial control. However, in modern conditions it is crucial to the effective operation of the organization.
L. V. Zavyalova +1 more
doaj
The Effect of Attentional Focus of Supra-Postural Task on Performance and Learning of Postural Control in Girls Aged between 9 and 12 [PDF]
Postural control is one of the important abilities in daily life and sport activities of human beings and the importance of focus of attention is always discussed in this issue.
Nastaran Naderirad +2 more
doaj +1 more source
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source

