Results 161 to 170 of about 3,821,363 (300)

Molecular Glue Degraders Enhance CAPRIN1‐Dependent Lysosomal Degradation of APP and Reduce Amyloid β in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
A new class of lysosome‐directed molecular glue degraders selectively enhance CAPRIN1–APP interactions, driving APP degradation and reducing amyloid‐β production in human neurons and Alzheimer's disease mouse models. This CAPRIN1‐dependent targeted protein degradation strategy reveals a previously unrecognized therapeutic approach for disrupting the ...
Sunghan Jung   +15 more
wiley   +1 more source

The interaction of territorial bodies of internal affairs with local bodies of executive power and local self-government bodies in the prevention of administrative offences: dissertation

open access: yes, 2006
Назар Ю.С. Взаємодія територіальних органів внутрішніх справ із місцевими органами виконавчої влади та органами місцевого самоврядування у профілактиці адміністративних правопорушень: автореферат дисертації на здобуття наукового ступеня кандидата ...
Назар, Ю.С., Nazar, Yu.S.
core  

Mechanically Robust, Self‐Healable, and Cryotolerant GelMA Hydrogel for Wearable Tactile Sensors with Enhanced Durability, Lifetime, and Environmental Stability

open access: yesAdvanced Science, EarlyView.
A mechanically robust, self‐healable, moisturizing, cryotolerant and adhesive GelMA hydrogel is developed by incorporating polyvinyl alcohol, acrylic acid, sodium tetraborate, and glycerol into GelMA matrix via a photoinitiated polymerization process. The hydrogel‐derived omni‐healable ionotronic pressure sensor can sensitively and consistently monitor
Zhikang Li   +16 more
wiley   +1 more source

Specific features of the professional motivation of the chiefs of the internal affairs bodies / S. A. Stulba

open access: yes, 2016
Стульба, С. А. Особенности профессиональной мотивации руководителей органов внутренних дел / С. А. Стульба // Вестник Академии МВД Республики Беларусь. - 2016. - № 2. - С.
Стульба, С. А.
core  

Organic Electrochemical Transistors for Neuromorphic Bioelectronics: Materials and Manufacturing Technologies

open access: yesAdvanced Science, EarlyView.
Organic electrochemical transistors bridge biological ionic signaling and neuromorphic computation through volumetric electrochemical gating. This review connects Organic mixed ionic–electronic conductor materials, device architectures, and manufacturing technologies to show how geometry, ion transport, and fabrication strategies program plasticity ...
Hyunjin Lee   +5 more
wiley   +1 more source

Sex‐ and Time‐Resolved Physiological and Gut Ecosystem Responses to a Food‐Grade Microbiome‐Targeted Intervention in Collegiate Endurance Athletes

open access: yesAdvanced Science, EarlyView.
In collegiate endurance athletes, a 6‐week randomized CPYE intervention yielded time‐ and sex‐dependent shifts in field‐based cardiorespiratory, metabolic, and redox indices, accompanied by changes in gut multi‐omics profiles. An exploratory extension during intensified training generates hypotheses warranting future validation.
Meng Zhang   +8 more
wiley   +1 more source

ENSURING OPENNESS AND TRANSPARENCY IN THE ACTIVITIES OF INTERNAL AFFAIRS BODIES: FOREIGN EXPERIENCE

open access: yes
In this article, the foreign experience of ensuring openness and transparency in the activities of internal affairs bodies, the opinions of legal scholars are studied, and suggestions and recommendations are developed by the ...
Umurzakov, Dilshod
core   +1 more source

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