Results 231 to 240 of about 407,487 (268)

Consistencia interna y estructura factorial del Perfil de Impacto de Salud Oral aplicado a la enfermedad periodontal en una muestra de población general de adultos mexicanos / Internal Consistency and Factor Structure of the Oral Health Impact Profile ...

, 2018
José Moral de la Rubia, Norma Idalia Rodríguez Franco   +1 more
openalex   +2 more sources

Artificial Receptor in Synthetic Cells Performs Transmembrane Activation of Proteolysis

Advanced Biology, EarlyView.
Transmembrane signaling is the hallmark of living cells and is among the highest challenges for the design of synthetic cells. Herein, an artificial receptor based on the chemistry of self‐immolative linkers is used to communicate information across the lipid bilayer, for transmembrane activation of enzymatic activity. Abstract The design of artificial,
Ane Bretschneider Søgaard, Kaja Borup Løvschall, Mireia Casanovas Montasell, Clara Bakkegaard Cramer, Pere Monge Marcet, Andreas Bøtker Pedersen, Josefine Hammer Jakobsen, Alexander N. Zelikin   +7 more
wiley   +1 more source

Light‐Triggered Protease‐Mediated Release of Actin‐Bound Cargo from Synthetic Cells

Advanced Biology, EarlyView.
TEV Prtoease‐mediated Releasable Actin‐binding Protein (TRAP) is a protein‐based platform consisting of a cargo tightly bound to reconstituted actin networks in synthetic cells which can be proteolyticly released from the bound actin, followed by its secretion through membrane translocation mediated by a cell‐penetrating peptide.
Mousumi Akter, Hossein Moghimianavval, Gary D. Luker, Allen P. Liu   +3 more
wiley   +1 more source

Distinct Network Morphologies from In Situ Polymerization of Microtubules in Giant Polymer‐Lipid Hybrid Vesicles

Advanced Biology, EarlyView.
The successful in situ polymerization of microtubules in giant polymer‐lipid hybrid vesicles is illustrated. The microtubules formed in the giant hybrid vesicles exhibit different morphologies including lumenal network formation and membrane association. Abstract Creating artificial cells with a dynamic cytoskeleton, akin to those in living cells, is a
Paula De Dios Andres, Mousumi Akter, Cecilie Ryberg, Brigitte Städler, Allen P. Liu   +4 more
wiley   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Scaling Up Synthetic Cell Production Using Robotics and Machine Learning Toward Therapeutic Applications

Advanced Biology, EarlyView.
Synthetic cells (SCs) hold great promise for biomedical applications, but manual production limits scalability. This study presents an automated method for large‐scale SC synthesis, integrating robotic liquid handling and machine learning‐driven high‐throughput characterization.
Noga Sharf‐Pauker, Ido Galil, Omer Kfir, Gal Chen, Rotem Menachem, Jeny Shklover, Avi Schroeder, Shanny Ackerman   +7 more
wiley   +1 more source

Toward Design Principles for Biomolecular Condensates for Metabolic Pathways

Advanced Biology, EarlyView.
Biomolecular condensates are membrane‐less compartments found through‐out nature which can serve as reaction crucibles for biochemical processes. This review explores the design strategies underlying how condensates can be used in biotechnology to enhance multistep enzyme cascades including enhancement by mass action and substrate channeling, and ...
Alain A.M. André, Nikita Rehnberg, Ankush Garg, Magnus Kjærgaard   +3 more
wiley   +1 more source

Elasticity of Diametrically Compressed Microfabricated Woodpile Lattices

Advanced Engineering Materials, EarlyView.
Modulus–porosity relationship is derived for woodpile lattices with struts under diametrical compression. The formula presented here that Young's modulus is proportional to the square of the volume fraction E˜ρ2$E \sim \left(\rho\right)^{2}$ is shown to be consistent with computations and laboratory experiments on 3D‐printed samples.
Faezeh Shalchy, Atul Bhaskar
wiley   +1 more source

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Skew and internal consistency.

Journal of Applied Psychology, 2006
The effects of skew on the standardized item alpha were examined with Monte Carlo techniques. Alphas computed from normal variables were compared with alphas from lognormal variables, ranks, and skewed versus normal Likert-type variables. The extent and direction of skew were varied, as was the size of the population interitem correlation (rho), the ...
Tammy Greer, William P. Dunlap, Samuel T. Hunter, Mitchell E. Berman   +3 more
openaire   +3 more sources

A Nonparametric Coefficient Of Internal Consistency

Multivariate Behavioral Research, 1976
This paper discusses a frequency based, nonparametric measure of internal test consistency, referred to herein as coefficient alphaτ, which allows facile measurement of the significance of differences in internal consistency between tests, administrations, or scoring methods.
Robert R. Trippi, Robert B. Settle
openaire   +3 more sources