Results 41 to 50 of about 1,517,445 (317)

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Internal Control and Audit of Economic Entities with Integrated Reporting

open access: yesВестник Кемеровского государственного университета. Серия: политические, социологические и экономические науки
The current economy has no single approach to internal control and internal audit: the patterns of their functioning and interaction remain unclear.
Dymova Irina, Karpova Ol'ga
doaj   +1 more source

METHODOLOGICAL ASPECTS OF THE INTERNAL CONTROL SYSTEM FORMATION

open access: yesСтатистика и экономика, 2016
The methodological aspects of the internal control system formation are stated in the article. The great attention is focused on the problems of financial statements misrepresentation. The basic principles and structure of the internal control system are
Larisa I. Egorova   +2 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

The expression of the elements of the internal control system graphical representation

open access: yesBuhalterinės Apskaitos Teorija ir Praktika, 2014
The results of the analysis of scientific literature showed that scientists disagree and do not share the same opinion on the expression of the elements of the internal control system.
Lukas Giriūnas, Jonas Mackevičius
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Methodology of Designing the System of Internal Bank Control

open access: yesВестник Российского экономического университета имени Г. В. Плеханова, 2020
The article deals with a brand new concept of methodology of designing (developing) the system of internal bank control. The authors use the system paradigm as a basic, key principle of methodology of designing and developing the system of internal bank ...
V. I. Karpunin   +2 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Audit of taxation in the internal control system

open access: yesУченые записки Российской академии предпринимательства, 2021
In this article the author investigates, de jure and de facto, aspects of tax auditing. Due attention is paid to the internal control system of the organization.
A. H. Hamzin, F. S. Rastegaeva
doaj  

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