Results 41 to 50 of about 816,808 (266)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Internal Controls and Internal Audit [PDF]
, 2019 Huawei is committed to its fight against embezzlement, waste, jobbery, and corruption amongst senior managers. It seeks to receive income from a single source. Huawei delegates authority to field offices, enabling them to have more autonomy and operate more flexibly and efficiently.
openaire +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
The organization of an internal control system at the entities of an oil and gas industry
Ученые записки Российской академии предпринимательства, 2021 The article focuses on the analysis of characteristics of the organization of the internal control system at the enterprises of oil and gas industry.
N. I. Ovcharova, N. V. Kazakova
doaj
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
GESTÃO DE RISCOS NAS UNIVERSIDADES E CENTROS UNIVERSITÁRIOS DO ESTADO DE SANTA CATARINA
Revista Gestão Universitária na América Latina, 2011 This paper analyzes and describes the adaptation and application of risk management and internal controls in Higher educational institution (HEI) of the Santa Catarina State as a necessary support to every institution‟s Control.
Célia de Souza Sedrez +1 more
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Studies and Scientific Researches: Economics Edition, 2018 The overall objective of this study was to establish the effects of internal controls on the financial performance of Asiacell as a telecommunication company in Kurdistan Region of Iraq.
Amanj Mohamed Ahmed +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Implementation of internal controls in supply chain management: A case study
Journal of Transport and Supply Chain ManagementBackground: Internal controls in the supply chain management (SCM) are very important as they are the checks and balances that ensure compliance with rules and regulations.
Yolandy Klein +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source