Results 131 to 140 of about 1,428,004 (304)

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento   +3 more
wiley   +1 more source

Game load dynamics in basketball: influence of playing position and match progression

open access: yesFrontiers in Physiology
ObjectivesThis study explored the variability of internal and external load in professional basketball as a function of playing position and match quarter.MethodsFourteen ACB League players were monitored across three official games using ultra-wideband ...
Sebastián Feu   +3 more
doaj   +1 more source

Damage and fracture in composite thin shells [PDF]

open access: yes
The effect of fiber fracture on the load carrying capability and structural behavior of a composite cylindrical shell under internal pressure is investigated.
Chamis, Christos C.   +2 more
core   +1 more source

Prognostic Value of Neurofilament Light Chain and Glial Fibrillary Acidic Protein in ALD‐Related Myelopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak   +4 more
wiley   +1 more source

Training vs. Competition: Load and Intensity Differences Between Multi-Feeding and Simulated Match Play in High-Level Youth Badminton Players

open access: yesApplied Sciences
Badminton is an intermittent sport with a diverse exercise profile that stresses both aerobic and anaerobic energy systems. The aim of this study was to compare the internal and external load profiles of multi-feeding (MF) drills and simulated match play
Francisco Alvarez-Dacal   +6 more
doaj   +1 more source

Love numbers for internal loading

open access: yes
Love numbers used in the paper "GRACE detection of rapid mass redistributions during a mineral phase transition in the deep mantle" by Gaugne et al., 2025.
openaire   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni   +19 more
wiley   +1 more source

The use of TRIMPS to quantify training load in small-sided games in handball

open access: yesE-balonmano.com: Revista de Ciencias del Deporte, 2016
The aim of this study was to examine the internal load of use by a single parameter which includes the two basic components of the training load, volume, in the form of minutes, and intensity by the percentage of heart rate (HR), to determine the ...
Manuel Alejandro Ortega-Becerra   +2 more
doaj  

Monitoring Internal Load in Women's Basketball via Subjective and Device-Based Methods: A Systematic Review. [PDF]

open access: yesSensors (Basel), 2023
Espasa-Labrador J   +5 more
europepmc   +1 more source

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and 1‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

open access: yesArthritis Care &Research, EarlyView.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension phase).
Fabrizio De Benedetti   +19 more
wiley   +1 more source

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