Peripheral endocrine-nutritional machine learning signature predicts short-term response to neoadjuvant immunochemotherapy in locally advanced gastric cancer. [PDF]
Li F +10 more
europepmc +1 more source
ABSTRACT Objective To determine whether integration of serum neurofilament light chain (NfL) and cortical dysfunction improves diagnostic accuracy in amyotrophic lateral sclerosis (ALS) when applied alongside the Gold Coast criteria (GCC). Methods In this prospective study, 148 participants with suspected ALS were recruited (101 ALS and 47 with ALS ...
Aicee Dawn Calma +16 more
wiley +1 more source
Serum Uric Acid in Chronic Kidney Disease as a Marker of Risk or a Modifiable Driver of Progression: A Systematic Review. [PDF]
Cook DE +7 more
europepmc +1 more source
ABSTRACT Objective Early risk stratification may support clinical decision‐making in spontaneous intracerebral hemorrhage (ICH). We aimed to develop and internally validate HAGIV, a score integrating frequency of imaging markers (FIM), a time‐adjusted non‐contrast computed tomography (CT) metric of hematoma expansion, with established predictors for 90‐
Lei Song +10 more
wiley +1 more source
Case Report: Bezoar-mimicking intraluminal gossypiboma causing small-bowel obstruction and chronic malabsorption 15 years after hysterectomy. [PDF]
Cazarez-Aguilar MA +8 more
europepmc +1 more source
Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova +9 more
wiley +1 more source
Immunohistochemical Surrogates for Molecularly Defined Renal Tumors. [PDF]
Mazzucchelli R +4 more
europepmc +1 more source
ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch +5 more
wiley +1 more source
Acidophil stem cell-like pituitary neuroendocrine tumors with heterogeneous PIT1/SF1 or LH lineage-marker expression: a clinicopathological study of three cases. [PDF]
Zheng H, Yang X, Zhang M, Chen W.
europepmc +1 more source
Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif +17 more
wiley +1 more source

