Results 51 to 60 of about 432,240 (255)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

TOXOPATHOLOGICAL STUDIES ON THE EFFECT OF FLUORIDE POLLUTION ON MALE AND FEMALE FERTILITY IN ADULT RABBITS [PDF]

open access: yesAssiut Veterinary Medical Journal, 2011
Twenty four (15 male and 9 female) albino rabbits were used for studying the effect of chronic sodium fluoride (NaF) administration in drinking water (7 and 10 mg/kg body wt/day) for 12 weeks on fertility. Animals showed signs of intoxication and finally
HANAA A. EL-HALLAWANY   +1 more
doaj   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

open access: yesFEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey   +4 more
wiley   +1 more source

Componentes corporais e órgãos internos de cordeiros Texel x Bergamácia, Texel x Santa Inês e Santa Inês puros, terminados em confinamento, com casca de café como parte da dieta Body components and internal organs of Texel x Bergamácia, Texel x Santa Inês and purebred Santa Inês lambs finished in fedlot, with of coffee hull as part of the diet

open access: yesRevista Brasileira de Zootecnia, 2003
Foram utilizados 12 cordeiros cruzas Texel x Bergamácia (TB), 12 cordeiros cruzas Texel x Santa Inês (TS) e 12 cordeiros puros Santa Inês (SI), confinados individualmente por 50 dias (dos 130 aos 180 dias de idade).
Iraides Ferreira Furusho-Garcia   +2 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Características quantitativas das partes do corpo não-integrantes da carcaça animal e desenvolvimento do trato gastrintestinal de bezerros da raça Holandesa alimentados com dietas contendo quatro níveis de concentrado Quantitative traits of parts of the body non integrate of the animal carcass and development of the gastrointestinal tract of Holsteins calves fed diets with four concentrate levels

open access: yesRevista Brasileira de Zootecnia, 1999
Trinta e dois bezerros da raça Holandesa, puros por cruzamento, variedade preto e branco, com, em média, 75 dias de idade e 78 kg PV inicial, divididos em dois grupos de PV de abate (grupo 1: 16 animais abatidos com 190 ± 10 kg PV e grupo 2: 16 animais ...
Ricardo Dias Signoretti   +5 more
doaj   +1 more source

An effect of the animal condition after gas stunning on quality of slaughter products from Large White pigs

open access: yesТеория и практика переработки мяса, 2020
The aim of the research was to establish an effect of gas stunning of pigs at slaughter on the condition of the internal organs and pork functional-technological characteristics.
A. A. Semenova   +3 more
doaj   +1 more source

Carcass characteristics and meat quality of weaned New Zealand rabbits supplemented with Moringa oleifera leaves meal

open access: yesItalian Journal of Animal Science, 2023
Moringa oleifera leaves (MOL) containing phytochemicals could be used to replace synthetic growth promoters to improve products quality in sustainable rabbit production.
Mankga William   +4 more
doaj   +1 more source

A Theory of International Organization

open access: yes, 2019
This book explains the design and development of international organization in the postwar period. It theorizes that the basic set up of an IO responds to two forces: the functional impetus to tackle problems that spill beyond national borders and a desire for self-rule that can dampen cooperation where transnational community is thin. The book reveals
HOOGHE, Elisabeth   +2 more
openaire   +3 more sources

Home - About - Disclaimer - Privacy