Results 41 to 50 of about 433,154 (256)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Ветеринария сегодня, 2021 Enzootic bovine leukosis has been an urgent problem of veterinary medicine both in the Russian Federation and abroad for more than a hundred years. A number of aspects have been studied quite deeply; however, there are still areas that require additional
E. S. Krasnikova +3 more
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Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Determining the activity of body meridians during static exercise
Здоров’я, спорт, реабілітація, 2019 The purpose of the work was to determine the means of acupuncture diagnosis according to the method of J. Nakatani, the effect of performing physical exercises on the body on an example of a static exercise, which is performed similarly to the Padmasana (
O.V. Musiyenko, N.P. Matsola, L. Mykhats
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
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Ukrainian Journal of Veterinary Sciences, 2023 The increasing level of anthropogenic environmental pollution and effective means to reduce the negative impact of xenobiotics on animal and human health is an urgent problem today.
Iuliana Popescu, Ihor Kalinin
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
THE EFFECT A LEVELS OF CINNAMON (CINNAMOMUM BURMANII) LEAVES EXTRACT IN THE DIET ON INTERNAL ORGANS WEIGHT AND ABDOMINAL FAT OF BROILERS [PDF]
Russian Journal of Agricultural and Socio-Economic Sciences, 2022 This research aims to determine the effect of level of Cinnamon (Cinnamomum burmanii) leaves extract on the diet to internal organs broilers. The study used an experimental method with a completely randomized design (CRD) with six treatments and four ...
Suyudi L., Sudjarwo E., Sjofjan O.
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