Results 71 to 80 of about 2,891,548 (204)
FEBS Open Bio, EarlyView.TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao +10 more
wiley +1 more source
Poultry Science: Thermal stress is a risk that threatens poultry welfare and productivity. Thermal manipulation during egg incubation is considered a prevention strategy used to mitigate the detrimental effects of high ambient temperatures on birds. This study aimed to
Ebtsam Iraqi +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa +4 more
wiley +1 more source
Morphofunctional Aspects of Internal Organs in Chronic Alcoholism [PDF]
, 2023 It has been established that in the structure of mortality in recent years, death from chronic alcoholism and acute alcohol intoxication, as well as associated complications, occupies a leading position, second only to mortality from cardiovascular ...
Halimova, Yu. S.
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk +10 more
wiley +1 more source
Animal Production: Indonesian Journal of Animal Production, 2019 The aim of this experiment was to identify the internal organs weight of 6-weeks old native chickens after treatment feed with l-threonine and l-tryptophan supplement.
Charles Venirius Lisnahan +1 more
doaj +1 more source
Internal organs alteration in patients with systemic scleroderma in the Republic of Moldova [PDF]
, 2017 Disciplina Reumatologie și nefrologie, USMF Nicolae Testemițanu, Spitalul Clinic RepublicanThe variants, frequency and time of onset of internal organ involvement since onset of systemic sclerosis have been studied in 200 patients.
Groppa, Liliana +5 more
core +1 more source
Gravity‐Dependent Modulation of Downbeat Nystagmus: Insights From Velocity‐Storage Dysfunction
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Downbeat nystagmus varies with head position, a phenomenon termed gravity‐dependent modulation. We aimed to clarify its mechanism using a velocity‐storage model. Methods In 10 patients with downbeat nystagmus due to cerebellar disorders, we recorded eye movements at different pitch‐ and roll‐axis head positions.
Ji‐Hyung Park +5 more
wiley +1 more source
AgricultureThe rapid increase in the global human population, particularly in Low-Income Food Deficit Countries (LIFDCs), causes severe food shortages. Food shortages are complex and can be linked to economic, environmental, social, and political variables ...
Thando Tenza +3 more
doaj +1 more source
Arthritis Care &Research, EarlyView.Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos +2 more
wiley +1 more source