Results 71 to 80 of about 3,171,097 (300)
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
Trinta e dois bezerros da raça Holandesa, puros por cruzamento, variedade preto e branco, com, em média, 75 dias de idade e 78 kg PV inicial, divididos em dois grupos de PV de abate (grupo 1: 16 animais abatidos com 190 ± 10 kg PV e grupo 2: 16 animais ...
Ricardo Dias Signoretti +5 more
doaj +1 more source
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk +10 more
wiley +1 more source
Gravity‐Dependent Modulation of Downbeat Nystagmus: Insights From Velocity‐Storage Dysfunction
ABSTRACT Objective Downbeat nystagmus varies with head position, a phenomenon termed gravity‐dependent modulation. We aimed to clarify its mechanism using a velocity‐storage model. Methods In 10 patients with downbeat nystagmus due to cerebellar disorders, we recorded eye movements at different pitch‐ and roll‐axis head positions.
Ji‐Hyung Park +5 more
wiley +1 more source
Psychological effectiveness of program of development of administrative capabilities of organs’ of internal affairs leaders [PDF]
Лапчук В. С. Психологічна ефективність програм розвитку управлінських здібностей керівників органів внутрішніх справ України / Лапчук Віталій Степанович, Барко Вадим Іванович // Юридичний бюлетень. - 2016. - Вип. 2. - С.
Барко, В. І. +3 more
core +1 more source
: Thermal stress is a risk that threatens poultry welfare and productivity. Thermal manipulation during egg incubation is considered a prevention strategy used to mitigate the detrimental effects of high ambient temperatures on birds. This study aimed to
Ebtsam Iraqi +5 more
doaj +1 more source
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh +5 more
wiley +1 more source

