Results 41 to 50 of about 3,498,652 (264)

«Failed State» and «Gray Areas» of World Politics:the Present Generation or Past

Сибирское юридическое обозрение, 2017
The article describes the criteria for ideas “failed state” and a “gray zone” of world politics. On the basis of States' implementation of the internal functions of the conclusion of the similarity of the past with the modern states and failed state ...
Elizaveta A. Pakhomova
doaj   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Dorian Gray ou Terceira Via européia

Meridiano 47, 2017
O presente artigo busca analisar a atuação dos partidos de esquerda nos países europeus, em especial na França.
VIRGILIO ARRAES
doaj  

Clinical, Histologic, and Serological Predictors of Renal Function Loss in Lupus Nephritis

Arthritis Care &Research, EarlyView.
Objective Kidney survival is the ultimate goal in lupus nephritis (LN) management, but long‐term predictors remain inadequately studied, requiring long‐term follow‐up. This study aimed to identify baseline and early longitudinal predictors of kidney survival in the Accelerating Medicines Partnership LN longitudinal cohort.
Shangzhu Zhang, Laurence Magder, Daniel Goldman, Judith A. James, Joel M. Guthridge, Carla Guthridge, Peter Izmirly, Jill P. Buyon, H. Michael Belmont, Richard A. Furie, Noa Schwartz, Chaim Putterman, Jennifer L. Barnas, Jennifer H. Anolik, Sarah French, Maria Dall'Era, Avi Z. Rosenberg, Jeffrey Hodgin, Dawit S. Demeke, the Accelerating Medicines Partnership Rheumatoid Arthritis and Systemic Lupus Erythematosus (RA/SLE) Network, Michelle Petri, Andrea Fava   +21 more
wiley   +1 more source

Rational Choice and EU Politics [PDF]

, 2007
[From the introduction]. Rational choice approaches to politics did not originate in the study of the European Union (EU), nor is ‘rational choice’ as such a theory of European integration or of EU politics.1 Rational choice, like constructivism, should ...
Pollack, Mark A.
core  

Itália

Meridiano 47, 2017
O presente artigo busca delinear os impactos políticos e conseqüências internacionais e regionais da ascensão de Silvio Berlusconi ao cargo de primeiro-ministro italiano.
VIRGILIO ARRAES
doaj  

India’s security approach and its space in global politics. [PDF]

Revista UNISCI
As India positions itself as a rising regional decolonial power by promoting its socio-cultural norms and carving out a new place for itself in the changing landscape of global politics, its internal landscape and security policy continue to exhibit ...
Vidushi Kaushik , John Doyle
doaj   +1 more source

Real‐World Safety and Effectiveness of JAK Inhibitors in Systemic Sclerosis: A Propensity‐Matched Study From the EUSTAR Cohort

Arthritis Care &Research, EarlyView.
Objective JAK inhibitors (JAKi) have shown promising effects in early‐phase studies of systemic sclerosis (SSc). We aimed to assess the safety and explore the effectiveness of JAKi compared to conventional immunosuppressants in SSc. Methods A longitudinal retrospective study of the European Scleroderma Trials and Research Group (EUSTAR) cohort was ...
Stefano Di Donato, Marie‐Elise Truchetet, Marco Minerba, Oliver Distler, Juan José Alegre Sancho, Yolanda Braun‐Moscovici, Christina Bergmann, Petros Sfikakis, Jeska K. de Vries‐Bouwstra, Murray Baron, Silvia Bellando‐Randone, Lorenzo Dagna, Christopher P. Denton, Madelon C. Vonk, Vanessa Smith, Ivan Castellvi, Gabriela Riemekasten, Andra Balanescu, Masataka Kuwana, Maria De Santis, Kamal Solanki, Anastas Batalov, Vahan Mukuchyan, Marco Matucci‐Cerinic, Yannick Allanore, Francesco Del Galdo, Michael Hughes, EUSTAR Collaborators   +27 more
wiley   +1 more source

O desafio da coalizão vermelho-verde na Alemanha

Meridiano 47, 2017
A partir de uma análise da atual situação política interna na Alemanha, o presente artigo busca analisar a atual política externa daquele país em sua nova fase.
Simon E. Michel Berger, Gustavo Henrique Cocentino Ramos   +1 more
doaj  

Ethiopia: The Impact of External Factors on the Security of the Country

Obrana a strategie, 2016
In last decade, Ethiopia witnesses so far unseen economic growth while the transformation to democracy more or less failed. Due to the fact that the Horn of Africa belongs to the most unstable regions in Africa, external factors play a significant role ...
Jan Záhořík, David Šanc
doaj   +1 more source