Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Internal quality assessment of blood components at Mansoura university blood transfusion center. [PDF]
Shahin D +3 more
europepmc +1 more source
Heterotropic regulation and negative homotropic cooperativity
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Application of sigma-based quality control rules for the efficiency of internal quality control. [PDF]
Choi H +4 more
europepmc +1 more source
Internal quality control and external quality assurance: a great past opens the way to a bright future. [PDF]
Plebani M.
europepmc +1 more source
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
Enhanced stability of simulated leukocytes for hematology internal quality control samples: A material improvement. [PDF]
Vo NN +6 more
europepmc +1 more source
ABSTRACT This article examines the evolving role of organizational leadership amidst the rapid advancements in artificial intelligence (AI). It explores a broadly experienced and documented crisis in leadership, due in part to the disruptive nature of AI and emerging technology.
Rachel Wlodarsky, Davin Carr Chellman
wiley +1 more source
Explainable AI and mobile imaging for non-destructive avocado ripeness and internal quality assessment to reduce food waste. [PDF]
Lee IH, Li Z, Ma L.
europepmc +1 more source
Model development and update of portable NIRS instrument for assessment of internal quality attributes of two navel orange varieties. [PDF]
Sun X, Deng D, Liu J, Feng S.
europepmc +1 more source

