Results 41 to 50 of about 175,253 (302)

Internal stresses in thin film technology

open access: yes, 2022
S.502-507A short survey on the problems connected with internal stresses in thin films is given. The following topics are dealt with: the effects of internal stresses on behaviour under mechanical or corrosive loading conditions, measurement methods, the
Schultrich, B.
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Internal stresses in polycrystalline zirconia: Microstructure effects

open access: yes, 2013
International audienceZirconium oxide layers are submitted to internal stresses that play a role in damage of the layer. If the first order stresses are usually measured or computed, the second order stresses are also important for damage prediction, but
Yao, Zhao Yue   +2 more
core   +1 more source

CONTROL OF THE SURFACE CONDITION OF STEEL PARTS RESTORED BY ELECTROLYTIC CHROMIUM-PLATING IN THE PROCESS OF REPAIR

open access: yesИзвестия высших учебных заведений: Нефть и газ, 2017
The article deals with peculiarities of restoration of steel parts by electrolytic chromium-plating depending on structural heterogeneity of worn surfaces.
I. M. Kovenskiy   +2 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

An experimental and computational investigation of bone cement residual stresses [PDF]

open access: yes, 2006
Hip arthroplasty is a common orthopaedic procedure with considerable success in alleviating hip joint pain and disability. To transfer loads from the prosthesis to the contiguous bone, self-curing polymethyl methacrylate, often referred to as bone cement,
Hingston, John A.
core  

Gradient material Pd-PdHx

open access: yesЛитьë и металлургия, 2018
There was analyzed videotape recording of palladium plate bending during its one-side saturation with hydrogen in experimental conditions of isothermal temperature 130 °С, step hydrogening up to РН2 = 0,01 МPа, 0,033, 0,05 МPа.
M. V. Goltsova   +2 more
doaj   +1 more source

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