Results 171 to 180 of about 15,932 (235)

Multiscale mechanisms of green concrete regulated by silicon-to-calcium ratio: Physico-mechanical properties, hydration structure, and durability performance. [PDF]

PLoS One
Lou J, Liang Y, Zha W, Su Q.
europepmc   +1 more source

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

Degradation Law and Experimental Study of High- Performance Shotcrete Under the Coupling Effect of Sulfate and Chloride Salt. [PDF]

Materials (Basel)
Yang J, Deng S, Li G, Dai X.
europepmc   +1 more source

Glucocorticoids Impair the Airway Epithelial Barrier via Autophagy‐Associated Apoptosis in Asthma: A Preliminary Study Both In Vitro and In Vivo

Pediatric Discovery, EarlyView.
Mechanism underlying the negative effects of glucocorticoids on the airway epithelial barrier. Glucocorticoids upregulate autophagy factors and downregulate anti‐autophagy factors. Enhanced autophagy promotes excessive apoptosis and epithelial detachment, impairing airway barrier function.
Hao You, Wenjing Zou, Tangqiaochu Gan, Yu Zhao, Jie Hu, Wen Tan, Ting Wang, Luo Ren, Zhengxiu Luo, Zhou Fu, Chao Niu   +10 more
wiley   +1 more source

Water-Soluble Epoxy Resins as an Innovative Method of Protecting Concrete Against Sulfate Corrosion. [PDF]

Materials (Basel)
Kostrzewski W, Laks I, Sybis M.
europepmc   +1 more source

Human Umbilical Cord Mesenchymal Stem Cell–Derived Exosomes Attenuate Renal Fibrosis by Suppressing Fibroblast Activation via the INHBA/PI3K/AKT Pathway

Pediatric Discovery, EarlyView.
MSC‐Exo derived from human umbilical cord (HucMSC‐Exo) downregulates INHBA expression, consequently modulating the PI3K/AKT signaling cascade. This regulation attenuates renal fibroblast activation and extracellular matrix deposition, thereby exerting a renoprotective effect against fibrosis.
Meiling Chen, Chenxi Jia, Zhuocheng Shi, Bianan Zhu, Yihang Yu, Xing Liu, Feng Liu, Jianwei Chen, Tao Xu, Yuanyuan Zhang, Deying Zhang, Guanghui Wei   +11 more
wiley   +1 more source

Study on the Durability of Graphene Oxide Concrete Composite Under Chloride and Sulfate Environments. [PDF]

Materials (Basel)
Gao Z, Shi Q, Cui J, Lin J, Mao W, Kosior-Kazberuk M, Krassowska J.   +6 more
europepmc   +1 more source

Dynamic Polydisulfide Latex via Emulsion Ring‐Opening Polymerization of Cyclodisulfides

Journal of Polymer Science, EarlyView.
A polydisulfide latex with a high molar mass was achieved by emulsion polymerization process starting from a dithiol. The mechanism reveals an entropy‐driven ring‐opening polymerization involving disulfide macrocycle intermediates. The polydisulfide particles can be degraded by thiol‐disulfide exchange, and the disulfide fragments can be reengaged in a
Sandric Afonso, Pierre‐Louis Quentin, Marc Schmutz, Cécile Joyeux, Cuong Minh Quoc Le, Abraham Chemtob   +5 more
wiley   +1 more source

Method to Predict Salt Expansion Deformation in Cement-Stabilized Macadam Under Sulfate Attack Based on Pore Evolution. [PDF]

Materials (Basel)
Li X, Mao X, He P, Wu Q.
europepmc   +1 more source

Betulinic Acid Enema Alleviates Colitis by Targeting Vitamin D Receptor to Protect the Intestinal Mucosal Barrier and Modulate Mucosa‐Associated Microbiota

Phytotherapy Research, EarlyView.
ABSTRACT Ulcerative colitis (UC) is a chronic inflammatory disease of the colon with limited effectiveness and safety of current drug therapies. Betulinic acid (BA) is a naturally occurring pentacyclic triterpenoid present in traditional Chinese medicines used clinically as retention enemas for UC, but its direct effects and mechanisms remain unclear ...
Lina Dong, Yuanxia Gao, Qian Li, Guangxin Chen, Dong Yang, Liping Zhao, Xiaojing Liu, Shumei Lin   +7 more
wiley   +1 more source