Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
PEG/Folic Acid Coloaded Er:Y<sub>2</sub>O<sub>3</sub> Upconversion Nanoparticles: Enhanced Internalization and Potential for High-Contrast Bioimaging in HCT-116 Cells. [PDF]
Butera E +14 more
europepmc +1 more source
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel +8 more
wiley +1 more source
Comparative Analysis of Methodological Aspects of the Study of Extracellular Vesicles and Extracellular Mitochondria: From Isolation to Internalization. [PDF]
Yunusova N +5 more
europepmc +1 more source
Alpha-Glucosidase of <i>Manduca sexta</i> Is an Entry Factor for <i>Daphnis nerii</i> Cypovirus-23. [PDF]
Yang J +10 more
europepmc +1 more source
Antibody-Drug Conjugates in Oncology: Principles, Clinical Development, and Future Directions. [PDF]
Cheng B +6 more
europepmc +1 more source
A cytokine receptor-targeting chimera toolbox for expanding extracellular targeted protein degradation. [PDF]
Kumru K +8 more
europepmc +1 more source
Insulin receptor trafficking and interactions in muscle cells. [PDF]
Cen HH +9 more
europepmc +1 more source
Nisin bacteriocin blocks T. denticola-triggered MMP2 activation and pathogen internalization via TLR2. [PDF]
Kamarajan P +6 more
europepmc +1 more source

