Results 61 to 70 of about 4,813,075 (293)

Closing the Empirical Loop: Autonomous AI Agents Conduct End‐to‐end Research With Human Participants

Advanced Science, EarlyView.
A multi‐agent AI system autonomously executes the complete scientific workflow, from hypothesis to manuscript, across three psychological studies involving 288 participants. The system designs experiments, collects real world data, develops analysis pipelines, and writes manuscripts with theoretical rigor comparable to experienced researchers.
Gabrielle Wehr, Reuben Rideaux, Amaya J. Fox, David R. Lightfoot, Jason Tangen, Jason B. Mattingley, Shane E. Ehrhardt   +6 more
wiley   +1 more source

Familial Risk and Sibling Mentalization: Links with Preschoolers' Internalizing Problems [PDF]

, 2016
The current study explored whether older sibling mentalization moderated the relationship between familial risk for internalizing symptoms and the development of future internalizing problems in the younger siblings.
Rodrigues, Michelle
core   +1 more source

Aberrant GRP78 Phase Transition Sustains Endothelial IRE1α Signaling and Drives Blood–Brain Barrier Failure in Cerebral Amyloid Angiopathy

Advanced Science, EarlyView.
Vascular Aβ40 corrupts GRP78 phase behavior in brain endothelial cells, sustaining IRE1α–TRAF2–JNK signaling and driving apoptosis, tight junction loss, and blood–brain barrier failure in cerebral amyloid angiopathy. Pharmacological IRE1α inhibition restores vascular integrity, reduces leakage, and improves functional outcomes, revealing a targetable ...
Honglin Zheng, Qiang Li, Haiyang Luo, Yapei Yuan, Na Zhang, Yongting Lu, Suying Duan, Jieshi Zhong, Hang Zhang, Chenyang Liu, Yaochong Zhang, Wenzhuo Zhao, Yaxuan Song, Tuo Wang, Si Yan, Yapeng Li, Han Liu, Yuan Gao, Zongping Xia, Yuming Xu   +19 more
wiley   +1 more source

Childhood emotional maltreatment and internalizing problems in a non-clinical sample of adolescents: a moderated-mediation model of insecure anxious attachment style and gender

Research in Psychotherapy
Childhood emotional maltreatment (abuse and neglect) may contribute to the development of internalizing problems in adolescence. However, the mechanisms explaining this association should be examined further.
Giorgio Falgares, Giulia Costanzo, Giovanna Manna, Dorian A. Lamis   +3 more
doaj   +1 more source

Temperament profiles associated with internalizing and externalizing problems in preadolescence [PDF]

, 2004
This study investigates how temperament factors are linked to internalizing and externalizing problems in a Dutch population sample of preadolescents (N = 2230).
Veenstra, René, Ormel, Johan, Oldehinkel, Albertine J., Winter, Andrea F. de, Hartman, Catharina A., Veenstra, René; id_orcid   +5 more
core   +2 more sources

CLRe: A Synergistic Dual‐Engine Framework for One‐Step Retrosynthesis Prediction

Advanced Science, EarlyView.
CLRe uses a contrastive difficulty score to order pretrained seq2seq fine‐tuning for retrosynthesis. Reaction embeddings define the ranking score, and a cumulative easy‐to‐hard schedule expands from the easiest subset to the full training set while earlier examples remain active.
Tianhao Su, Xitao Wang, Musen Li, Guanhua Qin, Shunbo Hu, Tong‐Yi Zhang   +5 more
wiley   +1 more source

Longitudinal internalizing psychopathology structure in a diverse community sample of Los Angeles adolescents from 9th to 12th grade

SSM - Mental Health
Purpose: Manifestations of internalizing symptoms vary developmentally, particularly during adolescence, but most taxonomies, including modern structural models of psychopathology, do not adequately account for this.
Katherine M. Keyes, Megan C. Finsaas, Catherine A. Gimbrone, Nora C. Kelsall, Ahuva L. Jacobowitz, Adam M. Leventhal, Andrew G. Rundle   +6 more
doaj   +1 more source

CoSP: Reconfigurable Metamaterial Inverse Design via Contrastive Pretrained Large Language Model

Advanced Science, EarlyView.
In this work, CoSP (contrastive multi‐state pretrain), an intelligent inverse design method for reconfigurable metamaterials based on a contrastive pretrained large language model, is proposed. Numerical experiments demonstrate that CoSP can design reconfigurable metamaterial structures for multi‐state, multi‐band optical responses, showing great ...
Shujie Yang, Yuqi Zhang, Xuzhe Zhao, Yansong Tang, Kaichen Dong   +4 more
wiley   +1 more source

Associations between adolescents’ internalizing problems and well-being: is there a buffering role of boys’ and girls’ relationships with their mothers and fathers?

BMC Public Health, 2021
Background Internalizing mental health problems (i.e., depression and anxiety symptoms) are known to be related negatively to adolescents’ well-being.
Chantie Charissa Luijten, Daphne van de Bongardt, Joran Jongerling, Anna Petra Nieboer   +3 more
doaj   +1 more source

The Emerging International Taxation Problems [PDF]

International Journal of Financial Studies, 2018
The problems of tax evasion and tax avoidance are as old as taxes themselves. Between 2015 and 2016 alone, many U.S. multinational corporations were involved in tax disputes with the European Commission. From a historical perspective, these disputes are unprecedented as they have resulted in tremendous amount of tax penalties. The most notable case was
Yang, James G. S., Metallo, Victor N. A.
openaire   +2 more sources