Results 181 to 190 of about 945,377 (291)

An Oral Antiviral Combination Against Severe COVID‐19 Enabled by the Synergistic Mechanisms of Action of Auranofin and Remdesivir

open access: yesAdvanced Science, EarlyView.
FDA‐approved anti‐inflammatory drug Auranofin inhibits SARS‐CoV‐2 replication by inhibiting viral Main protease activity and Spike processing required for viral entry. It shows strong synergy with nucleoside analogue Remdesivir, due to non‐overlapping mechanisms.
Oyahida Khatun   +13 more
wiley   +1 more source

µSlicer for Programmable Multimaterial 3D Printing

open access: yesAdvanced Science, EarlyView.
ABSTRACT Nature rarely builds with uniform materials; instead, it achieves exceptional performance by arranging composition and structure across multiple length scales. Mimicking such architectures has become increasingly feasible with additive manufacturing, and especially with multimaterial 3D printing, where complex structures with spatially varying
Daniel H. Meile   +5 more
wiley   +1 more source

Psychometric validation and optimal cut-point determination of the Hausa WHO-5 well-being index for depression screening among internally displaced persons. [PDF]

open access: yesGlob Ment Health (Camb)
Duke AEE   +12 more
europepmc   +1 more source

Phosphonium Ionic Liquids for Electrochemical Energy Storage: Structure–Property–Interphase Relationships and Design Rule

open access: yesAdvanced Science, EarlyView.
Phosphonium ionic liquids offer a versatile platform for safer and more durable energy storage. This Review connects cation–anion structure with solvation, ion transport, electrochemical stability, and interphase formation across diverse battery chemistries.
Amir Haghipour   +7 more
wiley   +1 more source

Metasurface‐Based Multidimensional Light‐Field Manipulation: From Technologies to Applications

open access: yesAdvanced Science, EarlyView.
Multidimensional metasurfaces enable versatile manipulation of multiple optical degrees of freedom, including phase, amplitude, polarization, wavelength, and orbital angular momentum. This review summarizes their fundamental mechanisms, emerging strategies for multidimensional light‐field control, and key applications in optical computing, imaging ...
Heliang Yin   +6 more
wiley   +1 more source

Comparative Evaluation of Chelator‐Conjugated Peptides for Lead‐Labeled SSTR2‐Targeted Theranostics: Integrated Computational Modeling and Preclinical Validation

open access: yesAdvanced Science, EarlyView.
The study integrates density functional theory with radiochemical and biological validation to compare DOTA‐, PSC‐, and DOTAM‐based chelator‐conjugates for 203Pb/212Pb theranostic applications. Distinct differences in metal coordination, electrostatic properties, conformational flexibility, cellular uptake, biodistribution, and dosimetry are identified
Jeongyun Kim   +12 more
wiley   +1 more source

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