Results 61 to 70 of about 14,171,614 (276)
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Vanderbilt International; Vol. 02, No. 02, Spring/Summer 2010
, 2010 Vanderbilt International is published by the Vanderbilt International Office.*Keegan Scholars Travel the World * The New American Experience * VU Athletes Get International ...
Vanderbilt International Office
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Vanderbilt International; Vol. 01 No. 01, Fall 2008
, 2008 Vanderbilt International is published by the Vanderbilt International ...
Vanderbilt International Office
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Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Vanderbilt International; Vol. 03 No. 01, Fall/Winter 2010
, 2010 Vanderbilt International is published by the Vanderbilt International ...
Vanderbilt International Office
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Domestic Courts and the Interpretation of International Law [PDF]
, 2019 In Domestic Courts and the Interpretation of International Law, Odile Ammann examines the methodology and reasoning which domestic courts, including Swiss courts, use to interpret international law.
Ammann, Odile, Ammann, Odile,
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Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Vanderbilt International; Vol. 01 No. 02, Spring/Summer 2009
, 2009 Vanderbilt International is published by the Vanderbilt International ...
Vanderbilt International Office
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