Results 41 to 50 of about 3,477,113 (302)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

A word from our Editor-in-Chief

Nonconventional Technologies Review, 2022
“Lucian Blaga” University of Sibiu was present between 26th to 28th of May 2022 at EUROINVENT 2022, the 14th International Invention Exhibition in Iași and the 8th edition of the ICIR EUROINVENT 2022 International Conference, events held at the Palace ...
Mihail Aurel Titu
doaj  

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Trusted CI Experiences in Cybersecurity and Service to Open Science

, 2019
This article describes experiences and lessons learned from the Trusted CI project, funded by the US National Science Foundation to serve the community as the NSF Cybersecurity Center of Excellence.
Adams, Andrew, Avila, Kay, Basney, Jim, Brunson, Dana, Cowles, Robert, Dopheide, Jeannette, Fleury, Terry, Heymann, Elisa, Hudson, Florence, Jackson, Craig, Kiser, Ryan, Krenz, Mark, Marsteller, Jim, Miller, Barton P., Peisert, Sean, Russell, Scott, Sons, Susan, Welch, Von, Zage, John   +18 more
core   +1 more source

Reducing NOx Emissions of Cargo Handling Equipment (CHE) with Humid Air Systems [PDF]

, 2020
The authors designed and tested a humid air system (HAS) for reducing NOx emissions of an LPG-powered forklift. The HAS uses distilled water and heat from the exhaust to generate steam that is injected into the intake air of the engine to increase ...
Bonifacio, Jeremy, Rahai, Hamid
core   +1 more source

International Energy Days 2022

, 2022
Thanks to the 1st Energy Days, which was held for the first time in 2021 COVID-19 Pandemic, we brought together the competent people in the field of renewable energy, academics with important studies on the subject, students and all those who care about the studies in this field for the first time.
Ünsal Çelimli, Derya Betül, Erkan Sultan, tosun, nurperihan, yoldaş, yeliz   +3 more
openaire   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Land and Water Carrying Capacity in Tourism Area of Nusa Penida, Bali [PDF]

, 2020
Environmental resources are very important in supporting tourism activities. As a developing tourism area Nusa Penida needs sufficient land and water resources.
Sudipa, Nyoman
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

ERS International Congress 2022: highlights from the Respiratory Infections Assembly

ERJ Open Research, 2023
The European Respiratory Society International Congress took place both in person, in Barcelona, Spain, and online in 2022. The congress welcomed over 19 000 attendees on this hybrid platform, bringing together exciting updates in respiratory science and
Radhika Banka, Kiarina Chichirelo-Konstantynovych, Katie L. Horton, Tetyana Konstantynovych, Merete B. Long, Melissa J. McDonnell, Oliver W. Meldrum, Mirae Park, Lidia Perea, Oksana Viltsaniuk, Holly R. Keir   +10 more
doaj   +1 more source