Results 51 to 60 of about 6,892,303 (288)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Comparison and Optimization Path of Quality Control Systems for Direct Carbon Emission Measurement Data in Thermal Power Plants

Energies
This study systematically compares thermal power direct carbon emission data quality control systems in China, the EU, and the U.S., quantifying differences and proposing optimization strategies.
Jingyu Lei, Feng Chen, Lei Liu, Zilong Liu, Xingchuang Xiong   +4 more
doaj   +1 more source

International comparison of sectoral energy- and labour-productivity performance; stylised facts and decomposition of trends [PDF]

This paper simultaneously explores trends in energy- and labour productivity for 14 OECD countries and 13 sectors over the period 1970-1997. A principal aim of this paper is to trace back macroeconomic productivity developments to developments at the ...
Henri de Groot, Peter Mulder
core  

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Household Portfolios: An International Comparison [PDF]

This paper presents an overview of the main findings of an international project on Household Portfolios coordinated by the authors. Contributions to the project deal with the state of the art in analytical, computational, and econometric methods of ...
Luigi Guiso, Michael Haliassos, Tullio Jappelli   +2 more
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Towards Net-Zero: Comparative Analysis of Hydrogen Infrastructure Development in USA, Canada, Singapore, and Sri Lanka

Fuels
This paper compares national hydrogen (H2) infrastructure plans in Canada, the United States (the USA), Singapore, and Sri Lanka, four countries with varying geographic and economic outlooks but shared targets for reaching net-zero emissions by 2050.
Myo Myo Khaing, Chuck Hookham, Janaka Ruwanpura, Shunde Yin   +3 more
doaj   +1 more source

An International Comparison of Employee Training [PDF]

This article uses data from the 1994 International Adult Literacy Survey (IALS) to examine employee training in the seven participating countries: Canada, the United States, Switzerland, the Netherlands, Poland, Germany, and Sweden.employee training ...
Kapsalis, Constantine
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Measuring the Efficiency of European Union Farms under Heterogeneous Technologies

Gospodarka Narodowa. The Polish Journal of Economics, 2020
The aim of the present study was to derive the characteristics of the production process for crop farms in the European Union member states. The paper uses regional data on farms taken from the Farm Accountancy Data Network (FADN).
Jerzy Marzec, Andrzej Pisulewski
doaj   +1 more source