Results 151 to 160 of about 406,807 (298)

Oral abstracts of the 21st International AIDS Conference 18-22 July 2016, Durban, South Africa

, 2016
Martin, GE, Pantazis, N, Hoffmann, M, Hickling, S, Hurst, J, Meyerowitz, J, Willberg, CB, Robinson, N, Brown, H, Fisher, M, Kinloch, S, Babiker, A, Weber, J, Nwokolo, N, Fox, J, Fidler, S, Phillips, R, Frater, J   +17 more
openalex   +1 more source

IgG‐Bridging–Seeded Synergistic Aggregation of SARS‐CoV‐2 Spikes Underlies Potent Neutralization by a Low‐Affinity Antibody

Advanced Science, EarlyView.
Low‐affinity antibodies are frequently disregarded in discovery pipelines. This work reports P5‐1C8, a Class 1 SARS‐CoV‐2 antibody with weak trimer binding (KD‐to‐IC50 > 3700‐fold) yet potent neutralization of Omicron JN.1. Structural, biophysical, functional, and coarse‐grained simulations collectively demonstrate that transient inter‐spike IgG ...
Niannian Lv, Peng Chen, Xiaobin Dai, Hu Xu, Ziheng Li, Zelin Shan, Jinqian Li, Fenglin Guo, Yuanfang Chen, Jiayi Li, Yiqian Huang, Guizhi Dong, Yifan Jiang, Liang Chen, Xuanyu Nan, Hanjun Zhao, Kang Zhang, Shilong Fan, Yuanchen Dong, Dongsheng Liu, Xinquan Wang, Deli Huang, Xiaojing Pan, Chunying Chen, Zhihua Liu, Li‐Tang Yan, Qi Zhang, Linqi Zhang, Yuliang Zhao, Yuhe Renee Yang   +29 more
wiley   +1 more source

Soil taxonomy proposals for acid sulfate soils and subaqueous soils raised by the 8th International Acid Sulfate Soils Conference

, 2017
Barret M. Wessel, John M. Galbraith, Mark H. Stolt, Martin C. Rabenhorst, Delvin S. Fanning, Maxine J. Levin   +5 more
openalex   +2 more sources

A Simplified Three‐Tailed N‐Alkyl Phosphoramidate Lipid Platform Enables Inguinal Adipose‐Accumulated mRNA Delivery for Anti‐Obesity Therapy

Advanced Science, EarlyView.
This study develops an mRNA therapy encoding a long‐acting GLP‐1/FGF21 fusion protein. A three‐tailed ionizable lipid engineered three‐component lipid nanoparticle delivers the mRNA to inguinal adipose tissue. In obese mice, this targeted, dual‐hormone treatment potently reduces body weight, fat mass, presenting a localized strategy for metabolic ...
Bin Ma, Yunxuan Liu, Huijuan Zhang, Yian Fang, Yizhe Xue, Junsheng Xue, Ziqiong Jiang, Tianyan Zhou, Yanyun Hao, Fei Xie, Lei Miao   +10 more
wiley   +1 more source

Engineering solids under pressure;: Papers presented at the Third International Conference on High Pressure, Aviemore, Scotland, 1970

, 1971
Hubert Lloyd David Pugh
openalex   +1 more source

Arginine Methylation Antagonizes TEAD3‐Mediated Repression to Promote Osteogenic Differentiation by Disrupting RUNX2‐Sequestrating Condensates

Advanced Science, EarlyView.
In the unmethylated state, TEAD forms stable, repressive condensates that sequester the osteogenic master regulator RUNX2. Arginine methylation of TEAD at R55 acts as a molecular brake, dissolving these condensates to release RUNX2 and activate the osteogenic program.
Lei Cao, Ruohui Han, Hui Xiong, Qian Li, Shaofei Tao, Xudong Wu, Dayong Liu   +6 more
wiley   +1 more source

Call for Papers - The Five Senses of Cinema

Cinéma & Cie, 2003
XI Udine International Film Studies Conference Udine
doaj  

Advancing CIK cell immunotherapy: highlights from the second international conference on DC-CIK and CAR-CIK approaches. [PDF]

Cancer Immunol Immunother
Sharma A, Sangiolo D, Rosato A, Pu J, Hou J, Tettamanti S, Serafini M, Fenix KA, Introna M, Rambaldi A, Ren X, Schmidt-Wolf IGH.   +11 more
europepmc   +1 more source

Effectiveness of Pre‐Transplant Dual GLP‐1 Receptor Agonist and SGLT2 Inhibitor Therapy on All‐Cause Mortality in Organ Transplantation Candidates with Obesity and Type 2 Diabetes: a Target‐Trial Emulation

Advanced Science, EarlyView.
This target trial emulation in solid organ transplant candidates with obesity and type 2 diabetes evaluates whether pre‐transplant dual therapy with GLP‐1 receptor agonists plus SGLT2 inhibitors is associated with post‐transplant mortality and kidney graft outcomes compared with monotherapy or usual care, using multinational electronic health records ...
Yu‐Nan Huang, Min‐Yu Tsou, Pin‐Hung Li, Jo‐Ching Chen, Yen‐Liang Liu, Gideon Meyerowitz‐Katz, Tsung‐Hsun Tsai, Pen‐Hua Su   +7 more
wiley   +1 more source

Concluding remarks of the Second International Conference on Aerobiology (Airborne Infection)

, 1966
Riley D. Housewright, Harold N. Glassman
openalex   +2 more sources