Results 61 to 70 of about 10,625,748 (303)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Security, Interventions, Distance, and Danger: New Publications, August 2015 [PDF]

open access: yes, 2015
A number of exciting open access publications have emerged from the Security in Transition team – a research programme which aims to conceptualise and empirically grasp the security gap both as a (perceived) reality and as a social mechanism within ...
International Development,
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Introducing the MSc Development Studies – James Putzel [PDF]

open access: yes, 2015
About the MSc Development ...
International Development,
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

MSc Development Studies Alumna wins the 2014 Global Development Network Next Horizon Essay Contest [PDF]

open access: yes, 2015
Congratulations to former MSc Development Studies student Susannah Robinson who has been chosen as one of the winners of the 2014 Global Development Network (GDN) Next Horizon Essay Contest.
International Development,
core  

AI-Powered Social Media for Development in Low- and Middle-Income Countries

open access: yesMedia and Communication
Social media powered by AI has become a major means for influencing beliefs and behaviors. Its unprecedented analytical, personalization, and scaling capabilities could transform economic, health, and other development outcomes in low- and middle-income ...
Borany Penh
doaj   +1 more source

Editors' Foreword

open access: yesStability : International Journal of Security and Development, 2012
The international policy community is preoccupied by a purported rise in fragility, conflict, and violence around the world. The World Bank´s 2011 World Development Report cast a spotlight on the many ways collective violence undermines governance and ...
Robert Muggah   +2 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Research Excellence Framework results now in – LSE tops tables! [PDF]

open access: yes, 2014
Research Excellence Framework results confirm that since 2009 the LSE’s International Development department has become established as one of the leading departments of International Development study in the ...
International Development,
core  

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