Results 181 to 190 of about 669,633 (262)

Introducing the 45-year special collection: Driving innovation in primary care scholarship. [PDF]

open access: yesS Afr Fam Pract (2004)
Von Pressentin KB   +6 more
europepmc   +1 more source

A phase 3, randomized clinical trial of soticlestat as adjunctive therapy for Lennox–Gastaut syndrome

open access: yesEpilepsia, EarlyView.
Soticlestat as adjunctive therapy for Lennox–Gastaut syndrome. Abstract Objective There remains a need for new treatments for Lennox–Gastaut syndrome (LGS), a developmental and epileptic encephalopathy with a heterogenous patient population that often requires polytherapy. The phase 3, randomized SKYWAY study (NCT04938427) investigated the efficacy and
Renzo Guerrini   +15 more
wiley   +1 more source

Serum NfL, GFAP, and p‐tau217 in adults with drug‐resistant epilepsy and intellectual disabilities: Signs of ongoing neural injury

open access: yesEpilepsia, EarlyView.
Abstract Objective Adults with epilepsy and intellectual disabilities (IDs) may be at increased risk of dementia, but clinical evaluation is complex and use of conventional biomarkers is often considered too invasive. We explored abnormality of serum neurofilament light chain (NfL), glial fibrillary acidic protein (GFAP), and phosphorylated tau‐217 (p ...
Hadassa Kwetsie   +10 more
wiley   +1 more source

Passing the baton. [PDF]

open access: yesSports Med Health Sci
Powers SK.
europepmc   +1 more source

Mortality in functional seizures: Evidence from a large electronic health records dataset

open access: yesEpilepsia, EarlyView.
Abstract Objective Several studies have found that people with functional seizures (FS) have increased mortality, approaching that of epilepsy (epileptic seizures [ES]). The small numbers of deaths in these studies make it unclear whether they can be attributed to comorbidities. We used a very large electronic health database to compare mortality in FS
Richard A. Kanaan   +4 more
wiley   +1 more source

Editorial: a year of growth and opportunity. [PDF]

open access: yesBr Paramed J
Williams J, Wilson C, McClelland G.
europepmc   +1 more source

A consensus roadmap for post‐traumatic epilepsy: Clinical biomarkers, research priorities, policy barriers, and pathways to interventional trials

open access: yesEpilepsia, EarlyView.
Abstract Understanding the mechanisms underlying post‐traumatic epilepsy (PTE) following traumatic brain injury (TBI), and developing strategies to prevent or modify its progression, has been the focus of large collaborative efforts within the epilepsy and TBI research communities for over a decade.
Elisa R. Zanier   +82 more
wiley   +1 more source

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