Results 41 to 50 of about 669,633 (262)

Design of Safe and Efficient Adenine Base Editors via Protein Language Model Screening for Osteoarthritis Treatment

open access: yesAdvanced Science, EarlyView.
ABSTRACT Base editors enable precise genome modification and have emerged as a promising therapeutic approach for correcting diseases caused by single‐nucleotide variants. While the current efficient version of adenine base editors (ABEs), such as ABE8e, exhibits exceptional efficiency for A‐to‐G conversions, their clinical translation is hindered by ...
Jiawei Yao   +12 more
wiley   +1 more source

Programmable RNA N6,2´‐O‐Dimethyladenosine Editing

open access: yesAdvanced Science, EarlyView.
ABSTRACT N6,2’‐O‐dimethyladenosine (m6Am) is a prevalent RNA modification located at the first transcribed nucleotide adjacent to the 5′ cap of mRNAs, where it has been implicated in gene regulation. However, the lack of methods for precise, transcript‐specific manipulation of m6Am has limited its functional dissection.
Yang Li   +9 more
wiley   +1 more source

Socio-hydrology: A New Perspective on Mountain Waterscapes at the Nexus of Natural and Social Processes

open access: yesMountain Research and Development, 2017
MountainViews ...
Marcus Nüsser
doaj   +1 more source

Sensor, Signal, and Imaging Informatics in 2017. [PDF]

open access: yes, 2018
Objective To summarize significant contributions to sensor, signal, and imaging informatics literature published in 2017.Methods PubMed® and Web of Science® were searched to identify the scientific publications published in 2017 that addressed sensors ...
Deserno, Thomas M   +3 more
core  

The Role of Artificial Intelligence in Medication Management for Older Adults: A Systematic Review

open access: yesAGING MEDICINE, EarlyView.
Artificial intelligence enhances medication management for older adults by improving adherence, personalizing treatment, and predicting risks. Despite benefits, challenges remain in usability, trust, ethics, and system integration. Successful adoption requires user‐centered design, ethical safeguards, and seamless healthcare integration to ensure safe,
Dipak Chandra Das   +9 more
wiley   +1 more source

Real‐World Treatment and Outcomes in Resectable Early‐Stage Non‐Small Cell Cancer: THASSOS‐INTL Australia Cohort

open access: yesAGING MEDICINE, EarlyView.
Australia cohort of THASSOS‐INTL; non‐interventional, multicenter, retrospective study provides insights into treatment patterns and associated survival outcomes in patients with resectable stage I‐III NSCLC in the pre‐immunotherapy era. Neoadjuvant and adjuvant therapy was reported in < 10% and < 40% patients, respectively.
Pei Ding   +4 more
wiley   +1 more source

Introduction: welcoming a new editorial board

open access: yesPSL Quarterly Review, 2014
The brief editorial note intriduces the new issue of the journal. Starting from the current issue (March 2014), the Review has a new international editorial board. The supervisory board and Economia civile (owner of the journal) wish to thank the friends
Carlo D'Ippoliti
doaj   +3 more sources

Monika Piątkowska as a Researcher in Sport Sciences and Sport Management

open access: yesPhysical Culture and Sport: Studies and Research, 2017
This is the fifth article of the cycle of portraits of the members of the Editorial Board and Editorial Advisory Board of the journal Physical Culture and Sport. Studies and Research.
Piątkowska Monika, Kosiewicz Jerzy
doaj   +1 more source

Disentangling the relationships between denomination of origin regulatory councils activities and Spanish wineries' export performance

open access: yesAgribusiness, EarlyView.
Abstract World markets for quality differentiated agri‐food products are highly competitive, presenting significant challenges for firms aiming to compete effectively. Government agencies and business organizations often implement various export promotion policies to address these challenges.
Nicolás Depetris‐Chauvin   +1 more
wiley   +1 more source

Robert Charles Schneider as a Proud Director of one of the First and Finest Higher Education Sport Management Programs in USA and World

open access: yesPhysical Culture and Sport: Studies and Research, 2017
This is the sixth article of the cycle of portraits of the members of the Editorial Board and Editorial Advisory Board of the journal Physical Culture and Sport. Studies and Research.
Schneider Robert C., Kosiewicz Jerzy
doaj   +1 more source

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