Results 41 to 50 of about 24,384 (260)

International Regimes of International Environmental Governance: Statement of the Problem

open access: yesМосковский журнал международного права, 2015
The necessity of formation of Inter-native modes of international environmental governance in the absence of a single, global environmental policy and environmental improvements despite conclusion of new international environmental treaties and ...
Mohammad Sarvar Anvar
doaj   +1 more source

Dispute settlement system under the World Trade Organization and borderlines of applicable law [PDF]

open access: yesZbornik Radova Pravnog Fakulteta u Nišu, 2016
The question of applicable law is of essence in discussing access to justice and legal protection under the WTO dispute settlement system because it determines which disputes are suitable for resolving under the WTO framework.
Zdravković Uroš
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Thai Law Enforcement of Obligations under the ASEAN Agreements on Environment

open access: yesChulalongkorn University Journal of Social Sciences
This research aims to study historical development and basic principles of obligations under the ASEAN agreements on environment in the ASEAN Social and Cultural Community (ASCC) and the measures of Thai law enforcement to comply with the obligations of ...
สุรพล ศรีวิทยา
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

International obligations in the sphere of protected natural areas' management's: compliance procedures

open access: yesRUDN Journal of Law, 2012
The article deals with key international environmental agreements and programs aimed at protecting national and transboundary protected natural areas. The authors identified special international non-compliance procedures under the provisions of these ...
I I Skripnik, A M Solntsev
doaj  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Non-compliance with the World Trade Organization agreements by exporters of the European bumblebee, Bombus terrestris

open access: yesSustainability: Science, Practice, & Policy, 2023
International companies commercially rear bumblebees worldwide, the trade of which is regulated through agreements established by the World Trade Organization (WTO).
Cecilia Smith-Ramírez   +5 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

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