Results 101 to 110 of about 22,736,035 (402)

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

Rubrics Methodology in Detail: Helping Save The Children Turn Children's Experiences of Discrimination and Exclusion into Rich, Trackable Outcomes

Journal of MultiDisciplinary Evaluation
Background: Save the Children’s child sponsorship program (referred to as Sponsorship) supports children, their families and communities, and institutions in 20 countries to create social and behavior change together so that all children survive, learn,
E. Jane Davidson, Thomaz Chianca, Nicole Dulieu, Anil Sigdel   +3 more
doaj   +1 more source

Depressive symptoms among women in Raqqa Governorate, Syria: associations with intimate partner violence, food insecurity, and perceived needs

Cambridge Prisms: Global Mental Health, 2019
Background.Raqqa Governorate, Syria has recently been affected by overlapping conflicts related to the Syrian Civil war and occupation by ISIS, resulting in widespread displacement and disruption of economic livelihoods.
K. L. Falb, A. Blackwell, J. Stennes, M. Hussein, J. Annan   +4 more
doaj   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

General service and child immunization-specific readiness assessment of healthcare facilities in two selected divisions in Bangladesh

BMC Health Services Research, 2018
Background Service readiness of health facilities is an integral part of providing comprehensive quality healthcare to the community. Comprehensive assessment of general and service-specific (i.e.
Md. Shajedur Rahman Shawon, Gourab Adhikary, Md. Wazed Ali, Md. Shamsuzzaman, Shahabuddin Ahmed, Nurul Alam, Katya A. Shackelford, Alexander Woldeab, Stephen S. Lim, Aubrey Levine, Emmanuela Gakidou, Md. Jasim Uddin   +11 more
doaj   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Practical challenges in data‐driven interpolation: Dealing with noise, enforcing stability, and computing realizations

International Journal of Adaptive Control and Signal Processing, EarlyView., 2023
Summary In this contribution, we propose a detailed study of interpolation‐based data‐driven methods that are of relevance in the model reduction and also in the systems and control communities. The data are given by samples of the transfer function of the underlying (unknown) model, that is, we analyze frequency‐response data.
Quirin Aumann, Ion Victor Gosea
wiley   +1 more source

An approach for coherent periodogram averaging of tilt‐series data for improved contrast transfer function estimation

FEBS Open Bio, EarlyView.
The contrast transfer function (CTF) is an imaging aberration that is a major resolution‐limiting factor in cryo‐electron microscopy (cryo‐EM). Precise CTF estimation is key to overcoming this limitation, but is particularly challenging in cryo‐electron tomography (cryo‐ET) data. Here, we present an approach for using geometric information to assist in
Sagar Khavnekar, William Wan
wiley   +1 more source

Characterising malaria connectivity using malaria indicator survey data

Malaria Journal, 2019
Malaria connectivity describes the flow of parasites among transmission sources and sinks within a given landscape. Because of the spatial and temporal scales at which parasites are transported by their hosts, malaria sub-populations are largely defined ...
Carlos A. Guerra, Daniel T. Citron, Guillermo A. García, David L. Smith   +3 more
doaj   +1 more source

What is the optimal assessment of speech? A multicentre, international evaluation of speech assessment in 2500 patients with a cleft. [PDF]

BMJ Open, 2023
Ombashi S, Kurniawan MS, Allori A, Sharif-Askary B, Rogers-Vizena C, Koudstaal M, Franken MC, Mink van der Molen AB, Mathijssen I, Klassen A, Versnel SL.   +10 more
europepmc   +1 more source