Results 61 to 70 of about 22,736,035 (402)

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

Midterm evaluation of DARCOF II. Increased production and closer relationships between organic and inherent qualities [PDF]

open access: yes, 2002
In October 2002 seven international scientists with expertise on organic farming performed an evaluation of the ongoing Danish research effort in organic food and farming (DARCOF II).
Andreasen, Claus Bo
core  

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

A clinical evaluation of the International Lymphoma Study Group classification of non-Hodgkin's lymphoma. The Non-Hodgkin's Lymphoma Classification Project.

open access: yesBlood, 1997
The recognition of several new types of non-Hodgkin's lymphoma (NHL) in recent years has led to proposals for changing lymphoma classifications, including a new proposal put forth by the International Lymphoma Study Group (ILSG).

semanticscholar   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Evaluating the Performance of International Mutual Funds

open access: yesFinancial Services Review, 1990
In this paper, the authors examine the performance of a sample of fifteen U.S.-based internationally diversified mutual funds between 1982 and 1988. Two performance measures are used, the Jensen measure and the positive period weighting measure proposed by Mark Grinblatt and Sheridan Titman.
Cumby, Robert E, Glen, Jack D
openaire   +2 more sources

IYV Global Evaluation [PDF]

open access: yes, 2002
This is a report on the global evaluation of the International Year of Volunteers (IYV)
Angela Ellis, Justin Davis Smith
core  

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

The cultivable endophytic fungal community of Scutellaria baicalensis: diversity and relevance to flavonoid production by the host

open access: yesPlant Signaling & Behavior, 2022
Scutellaria baicalensis (SB), a traditional Chinese medicinal plant, is widely used because of its important pharmacological activities. However, the endophytic fungi that promote flavonoid accumulation in SB remain unclear.
Xiao-Xuan Cui   +4 more
doaj   +1 more source

Firelight Foundation: An interim evaluation report of the Early Learning Innovation Fund [PDF]

open access: yes, 2015
The Hewlett Foundation in 2014 selected Management Systems International (MSI) to implement a midterm evaluation of the Early Learning Innovation Fund.
Jeff Davis   +3 more
core  

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