Results 71 to 80 of about 22,736,035 (402)

Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock, 2012

Intensive Care Medicine, 2013
ObjectiveTo provide an update to the “Surviving Sepsis Campaign Guidelines for Management of Severe Sepsis and Septic Shock,” last published in 2008.DesignA consensus committee of 68 international experts representing 30 international organizations was ...
R. Dellinger, M. Levy, A. Rhodes, D. Annane, H. Gerlach, S. Opal, J. Sevransky, C. Sprung, I. Douglas, R. Jaeschke, T. Osborn, M. Nunnally, S. Townsend, K. Reinhart, R. Kleinpell, D. Angus, C. Deutschman, F. Machado, G. Rubenfeld, S. Webb, R. Beale, J. Vincent, R. Moreno, The Surviving Sepsis Campaign Guidelines Committee inc Subgroup   +23 more
semanticscholar   +1 more source

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

Molecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci, Izzet Akiva, Yavuz Hakan Ozon, Hakan Berkil, Huseyin Karadayi, Omer Dizdar, Suayib Yalcin   +6 more
wiley   +1 more source

The effects of agricultural output market access interventions on agricultural, socio‐economic, food security, and nutrition outcomes in low‐ and middle‐income countries: A systematic review

Campbell Systematic Reviews
Background An estimated two billion people do not have sufficient access to nutritious food, and nearly half are dependent on small‐scale and subsistence farming.
Pierre Marion, Etienne Lwamba, Andrea Floridi, Suvarna Pande, Megha Bhattacharyya, Sarah Young, Paul Fenton Villar, Shannon Shisler   +7 more
doaj   +1 more source

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

8th AfrEA International Conference edition editorial

African Evaluation Journal, 2018
No abstract available.
Mark Abrahams, Florence E. Etta, Michele Tarsilla, Kambidima Wotela   +3 more
doaj   +1 more source

Report on evaluation of the revision of council regulation (EEC) NO 2092/91, import regime in two exporting non-EU countries (TR, CH) and on an international level [PDF]

, 2011
This report provides an evaluation of the new EU import regulation for organic products (Council Regulation (EC) 834/2007, Commission Regulation (EC) No 1235/2008).
Abay, Canan, Boyacı, Murat, Huber, Beate, Karahan Uysal, Ozlem, Miran, Bülent, Stolze, Matthias   +5 more
core  

Building an Expert System for Evaluation of Commercial Cloud Services

, 2013
Commercial Cloud services have been increasingly supplied to customers in industry. To facilitate customers' decision makings like cost-benefit analysis or Cloud provider selection, evaluation of those Cloud services are becoming more and more crucial ...
Cai, Rainbow, Li, Zheng, O'Brien, Liam, Zhang, He   +3 more
core   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Effective interventions for improving routine childhood immunisation in low and middle-income countries: a systematic review of systematic reviews

BMJ Open
Objective An umbrella review providing a comprehensive synthesis of the interventions that are effective in providing routine immunisation outcomes for children in low and middle-income countries (L&MICs).Design A systematic review of systematic ...
Shradha S Parsekar, Monica Jain, Shannon Shisler, Maren Duvendack, Maria Daniela Anda Leon   +4 more
doaj   +1 more source

Diagnosis, evaluation, and management of acute kidney injury: a KDIGO summary (Part 1)

Critical Care, 2013
Acute kidney injury (AKI) is a common and serious problem affecting millions and causing death and disability for many. In 2012, Kidney Disease: Improving Global Outcomes completed the first ever, international, multidisciplinary, clinical practice ...
J. Kellum, N. Lameire
semanticscholar   +1 more source