Results 131 to 140 of about 72,383 (252)

A Non‐Canonical Role of SMAD4 in Regulating 3D Genome Architecture to Inhibit Lung Squamous Cell Carcinoma Development

Advanced Science, EarlyView.
SMAD4 is identified as a guardian of 3D genome architecture in lung squamous cell carcinoma. Loss of SMAD4 unleashes EP300 at chromatin loop anchors, strengthening enhancer–promoter looping and H3K27ac at the SOX2 locus to drive aberrant SOX2 activation and tumor cell proliferation.
Qian Tang, Chen Lian, Xinyan Han, Xuhan Zhang, Zihan Wang, Boyu Wang, Taoyu Zhu, Xinrui Lin, Xiaolei Wang, Yaping Xu, Manyu Xiao, Zijin Wang, Junming Li, Silin Chen, Yunze Wang, Yufei Liu, Songsong Li, Zuolin Shen, Xi Lu, Xueqi Han, Yilu Zhou, Mingyang Xiao, Jiayi Ran, Xiaoran Cao, Xinyi Xu, Hugo Sámano‐Sánchez, Alfredo Rodríguez, Lian Wang, Shuifang Chen, Zhanyu Xu, Shirong Zhang, Nuo Yang, Yong Tang, Jian Liu   +33 more
wiley   +1 more source

Land Finance and fiscal rules: An estimated DSGE model for Hong Kong. [PDF]

PLoS One
Zhang W, Liu Z.
europepmc   +1 more source

Metal‐Support Interaction Triggered Electronic Reconstruction in Pd/CoN‐Co4N Catalysts for Optimizing MEK Oxidation and Poisoning Resistance

Advanced Science, EarlyView.
The strengthened EMSI in Pd/CoN‐Co4N induces electronic rearrangement, generating abundant Pd0 species in situ, modulating the Pd d‐band center to enhance O2 adsorption and MEK activation. Concurrently, it creates numerous Lewis acid sites that preferentially adsorb poisons and shield the active sites.
Yadi Wang, Chaoqian Ai, Cai Wang, Zeyu Jiang, Jialei Wan, Jingjing Wang, Xiangbo Feng, Chi He   +7 more
wiley   +1 more source

Government attention allocation in promoting strategic emerging industries in China's less-developed central region: A policy text analysis of Shanxi province. [PDF]

PLoS One
Li X.
europepmc   +1 more source

A General Enzymatic Strategy for Site‐Specific Incorporation of Modified Genetic Building Blocks Into DNA

Advanced Science, EarlyView.
Eco‐friendly enzymatic synthesis of high‐fidelity, site‐specifically modified DNA using 3′‐blocked nucleotides for full synthetic control and next‐generation sequencing compatibility. ABSTRACT Methods for site‐specific incorporation of modified DNA building blocks remain limited.
Raveena Raveena, Bhavana Ramadas, Sidney Becker   +2 more
wiley   +1 more source

The role of community energy in mediating sustainable energy transitions in East and Southern Eastern Africa. [PDF]

Npj Clean Energy
Castán Broto V, Gebreslassie M, Bekele G, Assefa A, Lake A, Habtu D, Bahta ST, Filli Nurhussien F, Gogoda C, Hara C, Howe L, Shenga C, Vallecha H, Mebrahtu AH.   +13 more
europepmc   +1 more source

All‐Flex Plasma Patch for In Vivo Delivery of Reactive Species

Advanced Science, EarlyView.
A fully flexible plasma patch enables stable, conformal treatment on complex biological surfaces and enhances transdermal delivery of reactive species. This platform achieves significant tumor suppression in vivo and reveals coordinated regulation of calcium signaling, metabolism, and programmed cell death, providing a promising strategy for safe and ...
Luxiang Zhao, Abulaihaiti Tuergong, Hanshu Yang, Shuang Xue, An Yan, Mingzhen Wang, Weilong Song, Wenzhe Si, Ruixue Wang   +8 more
wiley   +1 more source

From theory to autonomy: a topic modelling study of quantum finance through the lens of Datatopia and TOE. [PDF]

Front Artif Intell
Desu VDSR, Vivek Raj SN.
europepmc   +1 more source

The Spatiotemporal Genetic Architecture of Seed Vigor in Upland Cotton

Advanced Science, EarlyView.
Leveraging the semi‐automated SeedRanger platform, we profiled the germination kinetics of 356 cotton accessions at a 30‐min interval. This high‐throughput phenomic approach delineated a temporal genetic network comprising 541 stage‐specific loci. Crucially, functional validation identified FLA2 as a pivotal, auxin‐modulated regulator that orchestrates
Luyao Wang, Jie Dai, Ting Zhao, Shengjun Zhao, Hongyu Wu, Jiaying Pan, Yupeng Hao, Ke Nie, Li Yu, Yumeng Zhu, Xiangyi Zhao, Kai Huang, Mengke Zhang, Yongyan Zhao, Yaping Jiang, Siyuan Wang, Yiling Pan, Yubing Chen, Yilai Lin, Wanghong Shi, Yayuan Deng, Jin Han, Jie Li, Xuan Long, Junbin Wang, Zhiyuan Zhang, Zegang Han, Zhanfeng Si, Lei Ju, Jun Li, Tianzhen Zhang, Ji Zhou, Xueying Guan   +32 more
wiley   +1 more source

Ultra-processed foods: challenging corporate power and promoting local food systems to reclaim health. [PDF]

Global Health
Carriedo A, Labbé M, Samuels TA, Buse K, Policy and Prevention Committee of the World Obesity Federation.   +4 more
europepmc   +1 more source