A thiol‐modified alginate hydrogel microsphere‐encapsulated enzyme‐probiotic biohybrid (AKK‐COD) system has been developed to address the spatiotemporal delivery and colonization challenges of small intestine‐targeted probiotic for lipid metabolism regulation. The system exerts sequential functions of intragastric protection, small intestinal adhesion,
Xiaolin Wu +10 more
wiley +1 more source
Multimodal deep learning for international investment arbitration outcome prediction and bilateral investment agreement negotiation strategy optimization. [PDF]
Wu H, Xu J.
europepmc +1 more source
This study introduces a dual‐regulation strategy utilizing a Mn‐doped Co3O4 support to enhance the activity and stability of low‐loading IrO2 catalysts for acidic water oxidation. Mn induces strong Mn─O covalency to reinforce the spinel lattice and activates Ir sites via interfacial electron transfer.
Zhe Liu +13 more
wiley +1 more source
WHO Collaborating Centres: a global scientific network. [PDF]
Doherty M +3 more
europepmc +1 more source
Inhibitory Decay and Supercritical Brain Dynamics During Sleep Deprivation
Sleep deprivation progressively shifts human brain dynamics from near‐critical toward supercritical states, as revealed by neuronal avalanche analysis of resting‐state fMRI. These changes track subjective sleep pressure rather than vigilance lapses and show marked network heterogeneity. A circuit model suggests that reduced inhibitory efficacy provides
Dai Zhang +6 more
wiley +1 more source
Sustainable surgical financing through philanthropy: an analysis of contributions to low- and middle-income countries (LMICs). [PDF]
Poh DCSC +8 more
europepmc +1 more source
Ascorbic Acid‐Engineered Interface Enables Universal DNA Functionalization on Gold Nanoparticles: Attenuating electrostatic repulsion and leveraging synergistic hydrogen‐bonding interactions significantly lowers the kinetic barrier for DNA adsorption, enabling rapid and sequence‐general functionalization of non‐thiolated DNA‐requiring only a single ...
Guangping Li +9 more
wiley +1 more source
Making scientific publishing more balanced and reversing the current dangerous drift to better support global environmental conservation and planetary health. [PDF]
Guidetti P +4 more
europepmc +1 more source
SMAD4 is identified as a guardian of 3D genome architecture in lung squamous cell carcinoma. Loss of SMAD4 unleashes EP300 at chromatin loop anchors, strengthening enhancer–promoter looping and H3K27ac at the SOX2 locus to drive aberrant SOX2 activation and tumor cell proliferation.
Qian Tang +33 more
wiley +1 more source
Prevalence and correlates of active transportation to campus among Canadian post-secondary students: evidence from the Canadian Campus Wellbeing Survey. [PDF]
Derkach L, Hou M, Wu C, Faulkner G.
europepmc +1 more source

