Global research trends and hotspots in digital health in hypertension: A comprehensive bibliometric analysis (1992-2025). [PDF]
Zhang H, Xing Y, Tang Q, Su J.
europepmc +1 more source
A genome‐wide CRISPR screen and identifies PIK3CA as a key regulator of lipid nanoparticle (LNP) uptake is performed. Modulating PIK3CA with small‐molecule inhibitor BAY1082439 enhanced LNP uptake, siRNA delivery, and gene silencing in a variety of epithelial cells, and improved therapeutic outcomes in vivo.
Wenhan Wang, Kangfu Chen, Zongjie Wang
wiley +1 more source
Comparative analysis of JCI and nationally accredited medical organizations with day surgical hospital. [PDF]
Kudabayev K +7 more
europepmc +1 more source
MARPLE: A Proximity‐Triggered CRISPR‐Cas13 Platform for Ultrasensitive Antibody Detection
MARPLE is a modular CRISPR‐Cas13 immunoassay that uses antibody‐induced proximity to trigger a toehold‐exchange reaction, releasing an RNA activator for Cas13. This one‐pot, isothermal architecture enables ultrasensitive (femtomolar) and highly specific detection of diverse antibodies, including therapeutic, pathogen‐specific, and cancer‐associated ...
Elena Spezzani +6 more
wiley +1 more source
Transforming higher education: Embracing gender diversity for an inclusive future. [PDF]
Govender I, Kaswa R, Nair A.
europepmc +1 more source
Synergistic Mn‐MOF Activation of Pistol Ribozymes for Cancer Immunotherapy
A Mn2+‐based metal–organic framework delivers a catalytic Pistol ribozyme for targeted PD‐L1 mRNA cleavage in tumor cells, with the released Mn2+ not only inducing immune activation in immune cells but also increasing the Pistol ribozyme catalytic activity.
Ming Zhao +10 more
wiley +1 more source
Origins of Graphite Resistivity: Decoupling Stacking Fault and Rotational Misorientation
Interfacial dislocations critically influence interlayer transport in van der Waals (vdW) materials, yet quantifying their individual contributions remains challenging. We measure graphite's c‐axis resistivity and develop a decoupling strategy, revealing a resistivity ratio of ∼4507:74:1 for rotational misorientations, stacking faults, and AB stacking,
Weipeng Chen +6 more
wiley +1 more source
Collaboration under pressure: sustaining One Health research teams in a post-COVID environment. [PDF]
Gasser RB.
europepmc +1 more source
Upping the Ante for Political Economy Analysis of the International Financial Institutions [PDF]
Thomas D. Willett
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