Results 111 to 120 of about 7,531,091 (355)

Severe acute respiratory syndrome (SARS): breathtaking progress [PDF]

open access: yes, 2003
Reports of a new severe respiratory disease, now defined as severe acute respiratory syndrome (SARS), began to emerge from Guangdong, in southern China, in late 2002.
Bhagani, S, Gillespie, SH, Hawkey, PM
core   +2 more sources

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

open access: yesFEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul   +3 more
wiley   +1 more source

Perfil del viajero internacional: el trabajo como motivo de viaje

open access: yesMedicina y Seguridad del Trabajo
Objetivos: describir la población a estudio y comparar el motivo de viaje laboral con el motivo turístico y con la Visita de Amigos o Familiares (VFRs) para estimar si existe un perfil de riesgo diferente.
M.ª Belén Robles García
doaj  

Victor Heiser and the Rockefeller Foundation as a Medium for the Intercolonial Transfer of Health Management Knowledge in Asia in the Era of the League of Nations [PDF]

open access: yes, 2016
Victor Heiser was in charge of Rockefeller programs in Asia and the Pacific (which his contemporaries called the "Pacific region") as Director for the East of the International Health Board (IHB) of the Rockefeller Foundation from 1915 to 1934.
Tomoko Akami
core  

International differences in self-reported health measures in 33 major metropolitan areas in Europe. [PDF]

open access: yes, 2012
The increasing concentration of populations into large conurbations in recent decades has not been matched by international health assessments, which remain largely focused at the country level.
Alastair H. Leyland   +45 more
core   +2 more sources

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

open access: yesFEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp   +13 more
wiley   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

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