Results 41 to 50 of about 2,161,173 (316)

MicroRNA 196a contributes to the aggressiveness of esophageal adenocarcinoma through the MYC/TERT/NFκB axis

Molecular Oncology, EarlyView.
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo, Carlos M. Martínez‐Cáceres, Manuel Bernabé‐García, Vicente Munitiz, David Ruiz de Angulo, Pascual Parrilla, Ángeles Ortiz, Luisa F. Martínez de Haro, María L. Cayuela   +8 more
wiley   +1 more source

A student-initiated and student-facilitated international health elective for preclinical medical students

Medical Education Online, 2010
Introduction: Global health education is becoming more important for developing well-rounded physicians and may encourage students toward a career in primary care.
Nirali Vora, Mina Chang, Hemang Pandya, Aliya Hasham, Cathy Lazarus   +4 more
doaj   +1 more source

Internal migration and health in China [PDF]

The Lancet, 2008
China has a highly mobile population of 140 million rural-to-urban migrants (10% of the total population) a number that is expected to increase in the coming decade. Migrants tend to follow a temporary and circular pattern moving between cities and provinces in search of improved opportunities.
Miguel A Salazar, Sarah Cook, Xiaojiang Hu   +2 more
openaire   +3 more sources

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Salud internacional: el nuevo desafío para la educación de enfermería International health: a new challenge to nursing education

Revista Latino-Americana de Enfermagem, 1998
Para identificar las actividades de salud internacional (SI) en escuelas de enfermería y analizarlas en forma preliminar, se utilizó una muestra de 110 escuelas norteamericanas y, paralelamente, se enviaron cuestionarios a 4 escuelas latinoamericanas y a
Maria da Gloria Miotto Wright, Denise M. Korniewicz, Charles Godue, Maricel Manfredi   +3 more
doaj   +1 more source

International nutrition and health. [PDF]

Danish medical bulletin, 2006
Malnutrition is the most important underlying determinant of global disease and death. Maternal undernutrition and too early introduction of complementary foods with low energy-nutrient density, lead to low birth weight, impaired growth and intellectual development, and high mortality due to infectious diseases.
openaire   +2 more sources

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

Ethical and Organizational Challenges in Providing Medical Сare to Refugees and Internally Displaced Persons: the Standpoint of International Non-Governmental Organizations

Здоровье мегаполиса
Introduction. The scale of humanitarian crises and forced migration continues to grow, increasing the need for medical care for refugees and internally displaced persons.
V. V. Tonkonog, S. Khmeidy, D. T. Ananchenkov   +2 more
doaj   +1 more source

English-based Pediatric Emergency Medicine Software Improves Physician Test Performance on Common Pediatric Emergencies: A Multicenter Study in Vietnam

Western Journal of Emergency Medicine, 2013
Introduction: Global health agencies and the Vietnam Ministry of Health have identified pediatric emergency care and health information technology as high priority goals. Clinical decision support (CDS) software provides physicians with access to current
Michelle Lin, Trevor N Brooks, Alex C Miller, Jamie L Sharp, Le Thanh Hai, Tu Nguyen, Daniel R Kievlan, Robert M Rodriguez, Ronald A Dieckmann   +8 more
doaj   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

Molecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski, Molly R. Danks, John P. Thomson, Morwenna Muir, Martin Lee, John C. Dawson, Ana T. Amaral, Juan Diaz‐Martin, David S. Moura, Javier Martin‐Broto, Ali Alsaadi, Donald M. Salter, Ailsa J. Oswald, Graeme Grimes, Larry Hayward, Ted R. Hupp, Karen Sisley, Paul H. Huang, Neil O. Carragher, Valerie G. Brunton   +19 more
wiley   +1 more source