This study investigates how CTCs survive varying shear stress during hematogenous metastasis. We uncover a self‐protection mechanism, by which non‐adherent CTCs adapt to high shearing milieu through accumulated cytoplasmic myosin‐mediated disruption of myosin‐actin binding, attenuating force transmission into chromatin to protect CTCs from shear ...
Cunyu Zhang +10 more
wiley +1 more source
Regulatory Legislation and Practice on Life-threatening Industrial Activities in Georgia and their Compliance with European Human Rights Standards [PDF]
The positive obligation to protect the right to life, as enshrined in Article 2 of the European Convention on Human Rights (ECHR/the Convention), extends to industrial activities that pose a danger to human life.
Konstantin Korkelia
doaj
Human Rights in the United States Human Rights in the United States: A Special Issue Celebrating the 10th Anniversary of the Human Rights Institute at Columbia Law School: Foreword [PDF]
This year marks the tenth anniversary of the founding of the Human Rights Institute (HRI) at Columbia Law School. Appropriately, it also marks the sixtieth anniversary of the Universal Declaration of Human Rights, the foundational instrument of the ...
Cleveland, Sarah, Powell, Catherine
core +1 more source
The threat of destitution as a deterrent against asylum seeking in the European Union [PDF]
The problematization of asylum has detrimentally impacted on the provision of support for asylum seekers in host countries. The threat of destitution has become instrumental in restrictive asylum policies and is increasingly used as a deterrent against ...
Da Lomba, Sylvie
core +3 more sources
Sustainable Materials Design With Multi‐Modal Artificial Intelligence
Critical mineral scarcity, high embodied carbon, and persistent pollution from materials processing intensify the need for sustainable materials design. This review frames the problem as multi‐objective optimization under heterogeneous, high‐dimensional evidence and highlights multi‐modal AI as an enabling pathway.
Tianyi Xu +8 more
wiley +1 more source
A realistic utopia? Critical analyses of The Human Rights State in theory and deployment: Guest editors’ introduction [PDF]
We introduce this special issue on Benjamin Gregg’s recent theory of a human rights state by contextualising it within current human rights scholarship and explicating its core claims, before we provide an overview of the eight contributions.
Gregg, Benjamin, Wolfsteller, Rene
core +1 more source
Interpretable machine learning reveals how composition and processing govern the formation and microstructural burden of Fe‐rich intermetallic compounds in recycled Al–Si–Fe–Mn alloys. By separating morphology selection from morphology‐conditioned burden partitioning, this framework shows that identical Fe contents can yield different intermetallic ...
Jaemin Wang +2 more
wiley +1 more source
Overlegalizing Human Rights: International Relations Theory and the Commonwealth Caribbean Backlash Against Human Rights Regimes [PDF]
This article raises the intriguing claim that international law can be overlegalized. Overlegalization occurs where a treaty\u27s substantive rules or its review procedures are too constraining of sovereignty, causing governments to engage in acts of non-
Helfer, Laurence R.
core +2 more sources
Memristive Physical Reservoir Computing
Memristors’ nonlinear dynamics and input‐dependent memory effects make them ideal candidates for high‐performance physical reservoir computing (RC). Based on their conductance modulation, memristors can be classified as electronic or optoelectronic types.
Dian Jiao +9 more
wiley +1 more source
The New Innovation Frontier? Intellectual Property and the European Court of Human Rights [PDF]
This article provides the first comprehensive analysis of the intellectual property case law of the European Court of Human Rights ( ECHR ). Within the last three years, the ECHR has issued a trio of intellectual property rulings interpreting the right ...
Helfer, Laurence R.
core +1 more source

