Results 101 to 110 of about 585,296 (377)

Optimization of the Nonclinical Biological Evaluation of Medical Devices Using Toxicologic Pathology Best Practices

open access: yesAdvanced Healthcare Materials, EarlyView.
Nonclinical evaluation of biological responses to implanted medical devices and combination products in animals is required to predict possible outcomes and risks in patients. This paper describes globally accepted pathology “best practices” that 1) effectively address ISO standards and current regulatory guidance for medical device development and 2 ...
Kathleen A. Funk   +6 more
wiley   +1 more source

From Protecting Lives to Protecting States: Use of Force Across the Threat Continuum [PDF]

open access: yes, 2019
The increasing prominence in recent years of non-international armed conflicts that extend across state borders has strained the traditional legal categories that we use to regulate state use of force.
Regan, Milton C.
core   +1 more source

INTERNATIONAL LAW OF WAR OR HUMANITARIAN LAW

open access: yesPravo, 2010
In the paper works of many authors dealing with the rules which regulate the relationships between the confronted sides in armed conflicts, there are often used the following names referring to these rules: international war law and international ...
Miloš Petrović
doaj  

Ultrasound‐Triggered Gelation for Restoring Biomechanical Properties of Degenerated Functional Spinal Units

open access: yesAdvanced Healthcare Materials, EarlyView.
This study introduces an innovative approach to treating intervertebral disc degeneration using ultrasound‐triggered in situ hydrogel formation. Proof‐of‐concept experiments using optimized biomaterial and ultrasound parameters demonstrate partial restoration of biomechanical function and successful integration into degenerated disc tissue, offering a ...
Veerle A. Brans   +11 more
wiley   +1 more source

International humanitarian law and the targeting of non-state intelligence personnel and objects [PDF]

open access: yes, 2020
This Article examines the targetability of individuals and organizations performing intelligence functions for a non-State group involved in an armed conflict.
Schmitt, Michael N.
core   +1 more source

The Contribution of the International Court of Justice to the Development of International Environmental Law: A Contemporary Assessment [PDF]

open access: yes, 2008
The article provides a detailed and up-to-date assessment of the contribution of the International Court of Justice (ICJ) to the development of International Environmental Law (IEL), including the potential in this respect of the cases currently pending ...
Marino Beiras, Marcos, Zakany, Szabolcs
core   +4 more sources

A Novel Microfluidic System for 3D Epidermis and Full‐Thickness Skin Growth for Nanoparticle Safety Assessment

open access: yesAdvanced Healthcare Materials, EarlyView.
This work presents a novel, dynamically perfused, configurable microfluidic system for epidermis‐only (E and full‐thickness skin (FT SoC) growth, emulating human skin structure and barrier function. Upon TiO2 nanoparticle exposure, the system reveals compromised barrier integrity, reduced metabolic activity, increased permeability, and chemokine‐driven
Samantha Costa   +7 more
wiley   +1 more source

Invisible injuries: concussive effects and international humanitarian law [PDF]

open access: yes, 2017
The concussive effects of weapons used on the modern battlefield can cause Traumatic Brain Injury (TBI). Indeed, TBI has been termed the "signature wound" of the ongoing conflicts in Iraq and Afghanistan.
Highfill, Chad, Schmitt, Michael
core   +1 more source

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